Recruiting

Observational Study

Sponsor:

University of South Alabama

Code:

NCT01890395

Conditions

Mitochondrial DAMP Levels in Surgical Patients

Eligibility Criteria

Sex: All

Age: 19 - 70+

Healthy Volunteers: Not accepted

Interventions

Blood draws

Study Details

Brief summary:

To identify patients who may be predisposed for developing MOF (multiple organ failure)by the sampling of blood.

Conditions

Mitochondrial DAMP Levels in Surgical Patients

Study ID

NCT01890395

Start date

Dec, 2012

Status verified date

Aug, 2018

Completion date

Dec, 2019

Anticipated

Primary completion date

Dec, 2019

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 19 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients @ USAMC undergoing surgical operations expected to have microcirculatory changes, i.e., CABG, open heart, aortic or other revascularizing operations, general surgical operations such as colon resections, bowel resections or any other surgical procedures in which the subject could be expected to or might develop multiple system organ failure.

Exclusion Criteria:

N/A

Study Design

Enrollment

80 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

other: blood collection

procedure: Blood draws as the intervention

Interventions

Blood draws

Blood sampling collected at 9 timepoints: pre-operative, during surgery X 3, immediately after surgery, 24 hrs post-op, 72 hrs post-op, 5 days and 7 days post

Primary outcome measure

  • correlation mitochondrial damps (mDAMPS) and multiple organ system failure [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

William O. Richards, MD

251-471-7993brichards@usouthal.edu

Locations

University of South Alabama Medical Center

Recruiting

Mobile, Alabama, United States, 36617

Contacts

William O. Richards, MD

251-471-7993brichards@usouthal.edu

Principal Investigator:

William O. Richards, MD

More Information

Sponsor

University of South Alabama

Last update posted

Aug 17, 2018

Last verified

Aug, 2018

Keywords

  • mitochondrial DAMPS

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of South Alabama on 2018-08-17.