Recruiting

Bariatric Surgery

Sponsor:

UCLA

Code:

NCT02024542

Conditions

Morbid Obesity

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Not accepted

Interventions

Surgery

Study Details

Brief summary:

Research the genetic and biomechanical markers of human adipose tissue on patients with morbid obesity. Additional tissue/fluid collection is also gathered during the time of surgery.

Conditions

Morbid Obesity

Study ID

NCT02024542

Start date

Feb, 2011

Status verified date

May, 2026

Completion date

Apr, 2035

Anticipated

Primary completion date

Apr, 2035

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Meet NIH Criteria for Bariatric Surgery
  • Between the Age of 18-55
  • Dyslipidemia controlled with medication
  • Impaired glucose metabolism or type 2 diabetes

Exclusion Criteria:

  • Uncontrolled Metabolic syndrome (uncontrolled diabetes, htn, dyslipidemia), one or all conditions.

Study Design

Enrollment

500 participants

Anticipated

Interventions and Outcome Measures

Arms

Weight Loss Surgery - Healthy

Patients consented to participate have met the NIH criteria for Bariatric Surgery and have completed the normal pre-operative work up including nutritional counseling, psychological evaluation, and all necessary studies to rule out other co-morbid conditions prior to surgery. Patients do not have metabolic syndrome.

Weight Loss Surgery - Metabolic Syndrome

Patients consented to participate have met the NIH criteria for Bariatric Surgery and have completed the normal pre-operative work up including nutritional counseling, psychological evaluation, and all necessary studies to rule out other co-morbid conditions prior to surgery. Patients have metabolic syndrome.

Interventions

Surgery

Patients wishing to participate in the research will complete all necessary pre-operative work-up labs, testing \& counseling, complete and sign the informed consent. During weight loss surgery a small amount of subcutaneous and omental fat will be collected for analysis, with subsequent blood collection post surgery for analysis.

Primary outcome measure

  • Tensile Strength of White Adipose Tissue [ Time Frame: July 2012 ]

Central Contacts and Locations

Central contacts

Mohamed R Ali, MD

916-734-7290mrali@ucdavis.edu

William H Smith, BS, CCRP

916-734-7820whsmith@ucdavis.edyu

Locations

University of California Davis Medical Center

Recruiting

Sacramento, California, United States, 95817

Contacts

William H Smith, BS, CCRP

916-734-7820whsmith@ucdavis.edu

Principal Investigator:

Mohamed R Ali, MD

More Information

Sponsor

University of California, Davis

Last update posted

May 18, 2026

Last verified

May, 2026

Keywords

  • Bariatric Surgery
  • Obesity
  • Metabolic syndrome
  • Diabetes
  • Liver Disease

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, Davis on 2026-05-18.