Recruiting

Chronic Total OcclusionProspective Global Registry for the Study of Chronic Total Occlusion Intervention

Sponsor:

Minneapolis Heart Institute Foundation

Code:

NCT02061436

Conditions

Coronary Artery Disease

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The goal of this multicenter, investigator initiated registry is to collect information on treatment strategies and outcomes of consecutive patients undergoing CTO PCI among various participating centers. The information collected will be used to determine the frequency of CTO PCI performed at the participating sites and examine the procedural strategies utilized, and the procedural (both immediate and during follow-up) outcomes.

Conditions

Coronary Artery Disease

Study ID

NCT02061436

Start date

Jan, 2012

Status verified date

Aug, 2026

Completion date

Jan, 2030

Anticipated

Primary completion date

Jan, 2030

Anticipated

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Patients undergoing CTO PCI at each of the participating centers.

Exclusion Criteria:

None

Study Design

Enrollment

2000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

procedural success of chronic total occlusion PCI [ Time Frame: discharge from the hospital after PCI, which usually happens the day after the procedure ]

Central Contacts and Locations

Central contacts

Emmanouil S Brilakis, MD, PhD

(214) 857-1547 esbrilakis@gmail.com

Locations

Little Rock VA Medical Center

Recruiting

Little Rock, Arkansas, United States, 72205

Contacts

Barry Uretsky, MD

Barry.Uretsky@va.gov

Principal Investigator:

Barry Uretsky, MD

San Diego VAMC and University of California

Recruiting

San Diego, California, United States, 92161

Contacts

Mitul Patel, MD

mpatel@ucsd.edu

Principal Investigator:

Mitul Patel, MD

Medical Center of the Rockies

Recruiting

Loveland, Colorado, United States, 80538

Contacts

Anthony Doing, MD

anthony.doing@uchealth.org

Principal Investigator:

Anthony Doing, MD

Memorial Hospital

Recruiting

Jacksonville, Florida, United States, 32216

Emory University Hospital- Emory Heart and Vascular Center

Recruiting

Atlanta, Georgia, United States, 30322

Wellstar Health System

Recruiting

Marietta, Georgia, United States, 30060

St. Vincent Heart Center

Recruiting

Indianapolis, Indiana, United States, 46260

Tulane University Heart and Vascular Institute

Recruiting

New Orleans, Louisiana, United States, 70112

Contacts

Suzanne Bowers, RN

5049882030 sbowers@tulane.edu

Nana Asafu-Adjaye

5049886508 nasafuad@tulane.edu

Principal Investigator:

Nidal Abi Rafeh, MD

Massachusetts General Hospital

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

Bobby Yeh, MD, MBA

RYEH@mgh.harvard.edu

Principal Investigator:

Farouc Jaffer, MD, PhD

Beth Israel Deaconess Medical Center

Recruiting

Boston, Massachusetts, United States, 02215

Contacts

Linda Valsdottir

6176327653 lvalsdot@bidmc.harvard.edu

Principal Investigator:

Robert W Yeh, MD, MBA

Henry Ford Medical Center

Recruiting

Detroit, Michigan, United States, 48202

Contacts

Khaldoon Alaswad, MD

kalaswa1@hfhs.org

Principal Investigator:

Khaldoon Alaswad, MD

Minneapolis Heart Institute

Recruiting

Minneapolis, Minnesota, United States, 55407

Contacts

Emmanouil S Brilakis, MD, PhD

612-863-3900 esbrilakis@gmail.com

Principal Investigator:

Emmanouil S Brilakis, MD, PhD

Minneapolis VA Healthcare System and University of Minnesota

Recruiting

Minneapolis, Minnesota, United States, 55417

Contacts

Santiago Garcia, MD

garci205@umn.edu

Principal Investigator:

Santiago Garcia, MD

Maimonides Medical Center

Recruiting

Brooklyn, New York, United States, 11219

Trinity Medical WNY

Recruiting

Buffalo, New York, United States, 14221

Columbia University

Recruiting

New York, New York, United States, 10032

Contacts

Dimitri Karmpaliotis, MD

dk2787@columbia.edu

Principal Investigator:

Dimitri Karmpaliotis, MD

Carolina East Medical Center

Recruiting

New Bern, North Carolina, United States, 28560

Contacts

David Jessup, MD

djessup@carolinaeasthealth.com

Principal Investigator:

David Jessup, MD

The Christ Hospital Ohio Heart & Vascular

Recruiting

Cincinnati, Ohio, United States, 45219

University Hospitals (UH) Case Western Reserve University

Recruiting

Cleveland, Ohio, United States, 44106

Cleveland Clinic

Recruiting

Cleveland, Ohio, United States, 44195

Kettering Health Network

Recruiting

Kettering, Ohio, United States, 45429

Oklahoma City VA Medical Center

Recruiting

Oklahoma City, Oklahoma, United States, 73117

Oklahoma Heart Institute at Hillcrest Medical Center

Recruiting

Tulsa, Oklahoma, United States, 74104

Providence Heart & Vascular Institute

Recruiting

Portland, Oregon, United States, 97225

University of Pittsburgh Medical Center Presbyterian

Recruiting

Pittsburgh, Pennsylvania, United States, 15213

Contacts

Catalin Toma, MD

(412) 647-6000 tomac@upmc.edu

Principal Investigator:

Catalin Toma, MD

WellSpan Heart & Vascular

Recruiting

York, Pennsylvania, United States, 17405

Tristar Centennial Medical Center

Recruiting

Nashville, Tennessee, United States, 37203

University of Texas Southwestern Medical Center

Recruiting

Dallas, Texas, United States, 75216

Contacts

Emmanouil S Brilakis, MD, PhD

esbrilakis@gmail.com

Principal Investigator:

Emmanouil S Brilakis, MD, PhD

VA Dallas Medical Center

Recruiting

Dallas, Texas, United States, 75216

Contacts

Emmanouil S Brilakis, MD, PhD

(214) 857-1547 esbrilakis@gmail.com

Shuaib Abdullah, MD

Shuaib.Abdullah@va.gov

Principal Investigator:

Emmanouil S Brilakis, MD, PhD

Baylor Heart and Vascular Hospital

Recruiting

Dallas, Texas, United States, 75226

Contacts

James Choi, MD

James.Choi@baylorhealth.edu

Principal Investigator:

James Choi, MD

Baylor Scott & White Research Institute-The Heart Hospital Baylor Plano

Recruiting

Plano, Texas, United States, 75093

Baylor Scott and White Research Institute/ The Heart Hospital Baylor Plano

Recruiting

Plano, Texas, United States, 75093

Contacts

Julie McCracken

469-814-4717 Julie.McCracken@bswhealth.org

Rachelle Winkle

469-814-4183 Rachelle.Winkle@bswhealth.org

Principal Investigator:

Elizabeth Holper, MD

The Heart Hospital Baylor Plano

Recruiting

Plano, Texas, United States, 75093

Contacts

Elizabeth Holper, MD

Elizabeth.Holper@bswhealth.org

Principal Investigator:

Elizabeth Holper, MD

St. Boniface General Hospital

Recruiting

Winnipeg, Manitoba, Canada, R3E 0W3

More Information

Sponsor

Minneapolis Heart Institute Foundation

Last update posted

Aug 19, 2026

Last verified

Aug, 2026

Keywords

chronic total occlusion, percutaneous coronary intervention

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Minneapolis Heart Institute Foundation on 2026-08-19.