Recruiting

Transbronchial Cryobiopsy

Sponsor:

Laval University

Code:

NCT02235779

Conditions

Interstitial Lung Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Transbronchial lung cryobiopsy

Study Details

Brief summary:

Evaluation of diagnostic yield, feasibility and safety of transbronchial lung cryobiopsies done via bronchoscopy in the investigation of interstitial lung disease in comparison with videothoracoscopy-assisted surgical lung biopsy.

Conditions

Interstitial Lung Disease

Study ID

NCT02235779

Start date

Aug, 2014

Status verified date

Mar, 2021

Completion date

Dec, 2021

Anticipated

Primary completion date

Dec, 2021

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Volunteer subjects with interstitial lung disease in whom a surgical lung biopsy is planned for diagnostic investigation.

Exclusion Criteria:

  • Aged less than 18 y.o.
  • Pregnancy
  • Known coagulatoin disorder or blood dyscrasia
  • Aaking antiplatelet agents other than aspirin or therapeutic anticoagulants drugs that cannot be safely discontinued to undergo lung biopsy
  • Arterial oxgen pressure less than 60 mmHg on more than 2 liters per minute oxygen
  • Known pulmonary hypertension defined as systolic PAP above 40 mmHg on echocardiography
  • Unable to provide informed consent

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Diagnostic

Interventions and Outcome Measures

Arms

other: Cryobiopsy

Interventions

Transbronchial lung cryobiopsy

Primary outcome measure

  • Overall diagnostic yield of cryobiopsy specimens in interstitial lung disease [ Time Frame: After biopsy (up to 24 months) ]

Central Contacts and Locations

Central contacts

Antoine Delage, MDCM

418-656-4747antoine.delage@criucpq.ulaval.ca

Locations

Institut universitaire de cardiologie et de pneumologie de Québec

Recruiting

Québec, Canada, G1V 4G5

Contacts

Antoine Delage, MDCM

418-656-4747antoine.delage@criucpq.ulaval.ca

Principal Investigator:

Antoine Delage, MDCM

More Information

Sponsor

Laval University

Last update posted

Mar 8, 2021

Last verified

Mar, 2021

Keywords

  • ILD
  • Pulmonary fibrosis
  • Cryobiopsy
  • Transbronchial

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Laval University on 2021-03-08.