Recruiting

Observational Study

Sponsor:

New York Medical College

Code:

NCT02249923

Conditions

Pulmonary Vascular Disease

Pulmonary Arterial Hypertension

Eligibility Criteria

Sex: All

Age: 0 - 21

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Patients are being asked to be in this research study because medical researchers hope that by gathering information about a large number of children with pulmonary hypertension over time, their understanding of the disease process will increase and lead to better treatment. Investigators believe that pulmonary hypertension in children is different than pulmonary hypertension in adults and this study will help us understand those differences.

Conditions

Pulmonary Vascular Disease

Pulmonary Arterial Hypertension

Study ID

NCT02249923

Start date

Oct, 2014

Status verified date

Feb, 2025

Completion date

Dec, 2031

Anticipated

Primary completion date

Dec, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 21

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • The subject's age of onset of pulmonary hypertension must be prior to age 18 years
  • The person providing consent must be able to read either Spanish or English.
  • The subject (and/or parent/legal guardian) must be able to provide informed consent

Exclusion Criteria:

  • Diagnosed with pulmonary hypertension after age 18
  • Refusal to sign informed consent

Study Design

Enrollment

2500 participants

Anticipated

Interventions and Outcome Measures

Arms

Pulmonary Arterial Hypertension

Primary outcome measure

  • Time to clinical worsening [ Time Frame: 12 months ]

Central Contacts and Locations

Central contacts

Erika B Rosenzweig, MD

914-493-6160Erika.BermanRosenzweig@wmchealth.org

Robin Mascotti

303-724-6513robin.mascotti@childrenscolorado.org

Locations

Stanford University Medical Center

Recruiting

Palo Alto, California, United States

Contacts

Rachel Hopper, MD

rhopper@stanford.edu

University California San Francisco

Recruiting

San Francisco, California, United States

Contacts

Roberta Keller, MD

roberta.keller@ucsf.edu

Children's Hospital Colorado

Recruiting

Aurora, Colorado, United States, 80045

Contacts

David D. Ivy, MD

Dunbar.Ivy@childrenscolorado.org

Robin Mascotti

Robin.mascotti@childrenscolorado.org

Johns Hopkins All Children's Heart Institute

Recruiting

Saint Petersburg, Florida, United States

Contacts

Grace Freire, MD

Gfreire1@jhmi.edu

Johns Hopkins Children's Center

Recruiting

Baltimore, Maryland, United States

Contacts

Jenny Schramm, MD

schrammj@jhu.edu

Boston Children's Hospital

Recruiting

Boston, Massachusetts, United States

Contacts

Mary Mullen, MD

Mary.Mullen@cardio.chboston.org

Columbia University Medical Center

Recruiting

New York, New York, United States

Contacts

Usha Krishnan, MD

usk1@cumc.columbia.edu

Cincinnati Children's Hospital Medical Center

Recruiting

Cincinnati, Ohio, United States

Contacts

Russel Hirsch, MD

russel.hirsch@cchmc.org

Children's Hospital of Philadelphia

Recruiting

Philadelphia, Pennsylvania, United States

Contacts

Catherine Avitabile, MD

AvitabileC@email.CHOP.EDU

Vanderbilt University Medical Center

Recruiting

Nashville, Tennessee, United States

Contacts

Eric Austin, MD

eric.austin@Vanderbilt.edu

Seattle Children's Hospital

Recruiting

Seattle, Washington, United States

Contacts

Delphine Yung, MD

delphine.yung@seattlechildrens.org

University of Alberta Edmonton

Recruiting

Edmonton, Alberta, Canada

Contacts

Angela Bates, MD

angela.bates@albertahealthservices.ca

More Information

Sponsor

New York Medical College

Last update posted

Mar 13, 2025

Last verified

Feb, 2025

Keywords

  • Pulmonary Arterial Hypertension (PAH)
  • Pulmonary Vascular Disease (PVD)
  • Registry
  • Pediatric

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by New York Medical College on 2025-03-13.