Recruiting

Cardiovascular Health

Sponsor:

University of Michigan

Code:

NCT02306200

Conditions

Aortic Aneurysm

Aortic Dissection

Bicuspid Aortic Valve (BAV)

Heart Failure

Cardiovascular Diseases

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

Conditions

Aortic Aneurysm

Aortic Dissection

Bicuspid Aortic Valve (BAV)

Heart Failure

Cardiovascular Diseases

Study ID

NCT02306200

Start date

Aug, 2013

Status verified date

Apr, 2026

Completion date

Aug, 2053

Anticipated

Primary completion date

Aug, 2053

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Any patient over the age of 18 who is able/willing to give informed consent
  • Patients <18 years of age with parental consent and assent (if assent is applicable for their age)
  • Diagnosis of:
  • aortic pathology potentially due to a known or suspected inherited condition
  • Idiopathic aortic aneurysm
  • Interesting of novel vascular pathology in the aorta or main branches
  • Family history of aortic or vascular disease
  • Other cardiovascular disease
  • Healthy controls with no apparent cardiovascular disease

Exclusion Criteria:

\- Not willing or able to sign the consent

Study Design

Enrollment

15000 participants

Anticipated

Interventions and Outcome Measures

Arms

Aortic Disease

Patients with a diagnosis of any form of Aortic Disease

Controls

Patients without a diagnosis of Aortic Disease

Primary outcome measure

  • Establishing a biobank of patients with Aortic Disease [ Time Frame: 40 years ]

Central Contacts and Locations

Central contacts

Lauren Humphrey-Stark, BS

7342324779ljeany@med.umich.edu

Jen McNamara, MS

734-232-6180jlmcnama@med.umich.edu

Locations

University of Michigan

Recruiting

Ann Arbor, Michigan, United States, 48109

Contacts

Lauren Humphrey-Stark, BS

734-232-4779ljeany@med.umich.edu

Jen McNamara, MS

734-232-6180jlmcnama@med.umich.edu

More Information

Sponsor

University of Michigan

Last update posted

Apr 29, 2026

Last verified

Apr, 2026

Keywords

  • Aorta
  • Abdominal Aortic Aneurysm (AAA)
  • Thoracic Aortic Aneurysm (TAA)
  • Bicuspid Aortic Valve (BAV)
  • Aortic Dissection

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Michigan on 2026-04-29.