Recruiting

Observational Study

Sponsor:

University of Washington

Code:

NCT02306668

Conditions

Dry Eyes

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses. Dry eye disease is thought to have an inflammatory basis and in the vast majority of cases the cause of the chronic inflammatory condition is unknown.

Conditions

Dry Eyes

Study ID

NCT02306668

Start date

Feb, 2014

Status verified date

Dec, 2014

Completion date

Dec, 2016

Anticipated

Primary completion date

Dec, 2016

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • dry eye syndrome with OSDI score greater than 60
  • control group with OSDI score less than 30

Exclusion Criteria:

  • recent history of contact lens wear
  • use of topical antibiotics or prescription eye medication in past 6 months
  • penetrating ocular surgery in the last 12 months
  • age less than 18 years

Study Design

Enrollment

80 participants

Anticipated

Interventions and Outcome Measures

Arms

Ocular surface discomfort

There are no interventions with this observational study

Primary outcome measure

  • Identification of bacteria or fungus from conjunctival swab [ Time Frame: 1 month ]

Central Contacts and Locations

Central contacts

Sue Rath, COT

206-897-4331raths@uw.edu

Locations

UW Medicine Eye Institute

Recruiting

Seattle, Washington, United States, 98104

Contacts

Sue Rath

raths@uw.edu

Principal Investigator:

Russell Van Gelder, MD, PhD

More Information

Sponsor

University of Washington

Last update posted

Dec 3, 2014

Last verified

Dec, 2014

Keywords

  • Dry eye

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Washington on 2014-12-03.