Recruiting

Observational Study

Sponsor:

University of Colorado, Denver

Code:

NCT02321007

Conditions

Pregnancy

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Accepted

Study Details

Brief summary:

The purpose of this study is to establish a tissue and data repository consisting of samples of human placentas, umbilical cord blood, and maternal blood, collected at the time of delivery. Specimens will be used in cellular, molecular, and functional studies to learn more about changes in placental structure and function, which can result in serious pregnancy complications and determine life-long health by programming the fetus for future metabolic and cardiovascular disease.

Conditions

Pregnancy

Study ID

NCT02321007

Start date

Sep, 2014

Status verified date

Feb, 2026

Completion date

Sep, 2031

Anticipated

Primary completion date

Sep, 2031

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy women delivering at term
  • Women with pregnancy complications such as:

  • pre-term birth,
  • intrauterine growth restriction,
  • diabetes, and
  • obesity.

Exclusion Criteria:

  • Women:

  • under stress,
  • experiencing pain of labor.
  • Pregnancies complicated by other pathologies.

Study Design

Enrollment

1250 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Collecting, processing, and archiving human specimens from 1250 subjects [ Time Frame: Specimens will be stored for 50 years in repository ]

Central Contacts and Locations

Central contacts

Anita Kramer

303-724-1653anita.kramer@ucdenver.edu

Locations

University of Colorado Hospital

Recruiting

Aurora, Colorado, United States, 80045

Contacts

Anita Kramer

303-724-1653anita.kramer@ucdenver.edu

Principal Investigator:

Thomas Jansson, MD, PhD

More Information

Sponsor

University of Colorado, Denver

Last update posted

Feb 13, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Colorado, Denver on 2026-02-13.