Recruiting

Miltenyi Device

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT02438904

Conditions

Blood And Marrow Transplantation

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Interventions

CD34 Positive Stem Cell Infusion

Miltenyi device

Study Details

Brief summary:

Objectives:

Primary Objective

To provide compassionate access to the Miltenyi device for CD34+ cell infusions to patients who experience poor graft function after stem cell transplantation (SCT).

Conditions

Blood And Marrow Transplantation

Study ID

NCT02438904

Start date

May 6, 2015

Status verified date

May, 2026

Completion date

May 1, 2027

Anticipated

Primary completion date

May 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1\) Patients who have poor or no graft function post stem cell transplantation.

Exclusion Criteria:

N/A

Study Design

Enrollment

200 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: CD34 Positive Stem Cell Infusion

Participants infused by vein with around 1 - 4 million/kg CD34+ selected cells. If the first infusion is not effective, an additional infusion may be given 4 - 6 weeks after the first infusion.

Interventions

CD34 Positive Stem Cell Infusion

Participants infused by vein with around 1 - 4 million/kg CD34+ selected cells.

Miltenyi device

Miltenyi device is used for CD34+ cell infusions) to patients who experience poor graft function after stem cell transplantation (SCT).

Primary outcome measure

  • Increased Graft Function after Stem Cell Transplantation (SCT) [ Time Frame: 4 weeks ]

Central Contacts and Locations

Central contacts

Elizabeth Shpall, MD

713-745-2161eshpall@mdanderson.org

Locations

University of Texas MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

May 20, 2026

Last verified

May, 2026

Keywords

  • Blood And Marrow Transplantation
  • Stem cell transplantation
  • SCT
  • Poor graft function
  • CD34+ cell infusion

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-05-20.