Recruiting

Observational Study

Sponsor:

University of British Columbia

Code:

NCT02464085

Conditions

Stroke

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Longitudinal evaluation of recovery

Study Details

Brief summary:

The main goal of this program of research is to advance our understanding of how the severely damaged brain changes over the first 12-months post stroke. The investigators will determine 'who recovers', 'who does not recover', and 'why'

Conditions

Stroke

Study ID

NCT02464085

Start date

Jul, 2015

Status verified date

Jan, 2017

Completion date

Dec, 2019

Anticipated

Primary completion date

Dec, 2018

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • adults aged 18 to 90 years;
  • sustained their first stroke;
  • demonstrate subacute (<1 month) and severe upper limb motor deficits (defined by a SAFE \[shoulder abduction and finger extension\] score of <5 out of 10 points); and
  • can follow single stage commands

Exclusion Criteria:

  • neurological condition other than stroke e.g., Parkinson's disease

Study Design

Enrollment

50 participants

Anticipated

Interventions and Outcome Measures

Arms

Longitudinal evaluation of recovery

Stroke survivors with subacute and severe upper limb disability

Interventions

Longitudinal evaluation of recovery

Stroke survivors will be assessed at four time frames post stroke to evaluate neuroplastic and clinical changes in arm recovery over the first 12-months post stroke.

Primary outcome measure

  • 3T Magnetic Resonance Imaging (MRI) [ Time Frame: up to 12-months ]

Central Contacts and Locations

Central contacts

Kathryn S Hayward, PT PhD

6048273369kathryn.hayward@ubc.ca

Lara A Boyd, PT PhD

6048273369lara.boyd@ubc.ca

Locations

University of British Columbia

Recruiting

Vancouver, British Columbia, Canada, V6T1Z3

Contacts

Kathryn S Hayward, PT PhD

6048273369kathryn.hayward@ubc.ca

Lara A Boyd, PT PhD

6048273369lara.boyd@ubc.ca

Principal Investigator:

Lara A Boyd, PT PhD

More Information

Sponsor

University of British Columbia

Last update posted

Jan 10, 2017

Last verified

Jan, 2017

Keywords

  • Stroke
  • Upper limb
  • Neuroplastic change
  • Longitudinal
  • Function

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of British Columbia on 2017-01-10.