Recruiting

Tracheal IntubationImproving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

Sponsor:

Children's Hospital of Philadelphia

Code:

NCT02493478

Conditions

Failed or Difficult Intubation, Sequela

Intubation; Difficult

Intubation Complication

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.

Conditions

Failed or Difficult Intubation, Sequela

Intubation; Difficult

Intubation Complication

Study ID

NCT02493478

Start date

Mar, 2010

Status verified date

Jan, 2026

Completion date

Jan, 2030

Anticipated

Primary completion date

Jan, 2030

Anticipated

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Primary advanced airway events (on patients of all ages) in the PICU, CICU, NICU, DR and ED including: Tracheal Intubation, Laryngeal mask placement, Emergency tracheostomy and/or cricothyrotomy
Failed extubation attempts or unplanned extubations that require re-intubation will be considered a new primary intubation.

Exclusion Criteria:

Primary advanced airway events (tracheal intubations, laryngeal mask placement, emergency tracheostomy and/or cricothyrotomy) in the Operating Suites.

Study Design

Enrollment

150000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

Change in number of tracheal intubation associated events (TIAEs) [ Time Frame: participants will be followed for the duration of their hospital stay, an expected average of 4 weeks ]

Central Contacts and Locations

Central contacts

Hayley Buffman, MPH

215-590-6772 buffmanh@chop.edu

Locations

Children's of Alabama at Birmingham

Recruiting

Birmingham, Alabama, United States, 35233

Contacts

University of Alabama at Birmingham Institutional Review Board

205-934-3789 irb@uab.edu

Principal Investigator:

Jordan Newman, MD

Phoenix Children's Hospital

Recruiting

Phoenix, Arizona, United States, 85006

Contacts

PCH IRB

602-933-1000 swalker@phoenixchildrens.com

Principal Investigator:

David Tellez, MD

Arkansas Children's Hospital

Recruiting

Little Rock, Arkansas, United States, 72202

Contacts

Office of Research and Sponsored Programs

501-686-5667 rcsanders@uams.edu

Principal Investigator:

Ronald C Sanders, MD

University of Colorado Hospital

Recruiting

Aurora, Colorado, United States, 80045

Contacts

John Heldens

303-724-5000 john.heldens@ucdenver.edu

Principal Investigator:

Rebecca Shay, MD

Yale New Haven Children's Hospital

Recruiting

New Haven, Connecticut, United States, 06510

Contacts

Stephen Latham, JD, PhD

203-785-4688 human.subjects@yale.edu

Principal Investigator:

Lindsay Johnston, MD

Yale-New Haven Children's Hospital

Recruiting

New Haven, Connecticut, United States, 06510

Contacts

John Giuliano, MD

john.giuliano@yale.edu

Nemours Children's Health, Delaware

Recruiting

Wilmington, Delaware, United States, 19803

Contacts

302-651-4200

Principal Investigator:

Kimberly McMahon

Emory University

Recruiting

Atlanta, Georgia, United States, 30322

Contacts

Pradip Kamat, MD

404-785-6397 pradip.kamat@choa.org

Children's Hospital of Georgia

Recruiting

Augusta, Georgia, United States, 30912

Northwestern Medicine Prentice Women's Hospital

Recruiting

Chicago, Illinois, United States, 60611

Contacts

312-926-2000

Principal Investigator:

Nicole Pouppirt

Riley Hospital for Children

Recruiting

Indianapolis, Indiana, United States, 46202

Contacts

317-944-5000

Principal Investigator:

Samer Abu-Sultaneh

Kentucky Children's Hospital

Recruiting

Lexington, Kentucky, United States, 40536

Contacts

Ashwin Krishna, MD

ashwin.krishna@uky.edu

Norton Children's Hospital - University of Louisville

Recruiting

Louisville, Kentucky, United States, 40202

Johns Hopkins Medicine

Recruiting

Baltimore, Maryland, United States, 21205

Contacts

Office of Human Subjects Research IRB

410-955-3008 jhmeirb@jhmi.edu

Principal Investigator:

Kate Deanehan

Boston Children's Hospital

Recruiting

Boston, Massachusetts, United States, 02115

Baystate Medical Center

Recruiting

Springfield, Massachusetts, United States, 01199

Children's Hospital and Medical Center

Recruiting

Omaha, Nebraska, United States, 68114

Dartmouth-Hitchcock Medical Center

Recruiting

Lebanon, New Hampshire, United States, 03766

Contacts

Sholeen Nett, MD

603-650-5000 sholeen.t.nett@hitchcock.org

Morristown Medical Center

Recruiting

Morristown, New Jersey, United States, 07960

Contacts

Atlantic Health System

973-971-5000 anita.richards@atlantichealth.org

Principal Investigator:

Christina Melchionne

Albany Medical College

Recruiting

Albany, New York, United States, 12208

Contacts

518-262-5521

Principal Investigator:

Ilana Harwayne-Gidansky

Oishei Children's Hospital

Recruiting

Buffalo, New York, United States, 14222

Contacts

Ryan Breuer, MD

ryankbreuer@gmail.com

Cohen Children's Medical Center

Recruiting

New Hyde Park, New York, United States, 11040

University of Rochester at Golisano Children's Hospital

Recruiting

Rochester, New York, United States, 14642

Stony Brook Children's Hospital

Recruiting

Stony Brook, New York, United States, 11794

Maria Fareri Children's Hospital (West Chester Medical)

Recruiting

Valhalla, New York, United States, 10595

Contacts

Simon Li, MD

914-493-5941 lis@WCMC.com

Duke Children's Hospital

Recruiting

Durham, North Carolina, United States, 27705

Contacts

Kyle Rehder, MD

919-681-3550 kyle.rehder@duke.edu

WakeMed Health & Hospitals

Recruiting

Raleigh, North Carolina, United States, 27610

WakeMed

Recruiting

Raleigh, North Carolina, United States, 27610

Contacts

Elizabeth Woodard, RN, PhD

919-350-8795 WakeMed_IRB_Office@wakemed.org

Principal Investigator:

Stephen D DeMeo, DO

Akron Children's Hospital

Recruiting

Akron, Ohio, United States, 44308

Cincinnati Hospital Medical Center

Recruiting

Cincinnati, Ohio, United States, 45229

Cleveland Clinic Childrens Hospital

Recruiting

Cleveland, Ohio, United States, 44106

Contacts

216-444-5437

Principal Investigator:

Sabine Iben

Nationwide Children's Hospital

Recruiting

Columbus, Ohio, United States, 43205

Contacts

Anthony Lee, MD

614-722-3449 Anthony.Lee@nationwidechildrens.org

Oregon Health and Science University

Recruiting

Portland, Oregon, United States, 97239

Contacts

Paula Vanderford, MD

vanderfo@ohsu.edu

Children's Hospital - Penn State Hershey

Recruiting

Hershey, Pennsylvania, United States, 17033

Contacts

Ashley Derbyshire, MD

aderbyshire@hmc.psu.edu

Penn State Health Milton S. Hershey Medical Center

Recruiting

Hershey, Pennsylvania, United States, 17033

Contacts

Kathleen May

717-531-5687 khay@hmc.psu.edu

Principal Investigator:

Kristen Glass, MD

Hospital of the University of Pennsylvania

Recruiting

Philadelphia, Pennsylvania, United States, 19104

The Children's Hospital of Philadelphia

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Children's Hospital of Philadelphia IRB Office

215-590-2830 irboffice@chop.edu

Principal Investigator:

Vinay Nadkarni, MD

Hasbro Children's Hospital

Recruiting

Providence, Rhode Island, United States, 02903

Contacts

Lee Polikoff, MD

lee.polikoff@lifespan.org

Dell Children's Medical Center - Ascension

Recruiting

Austin, Texas, United States, 78723

Contacts

512-324-0000

Principal Investigator:

Hunter Daigle

Medical City Children's Hospital

Recruiting

Dallas, Texas, United States, 75230

Contacts

Kris Bysani, MD

KrisBysani@gmail.com

Baylor - Christus Children's - Main Hospital

Recruiting

Irving, Texas, United States, 75039

Contacts

Baylor College of Medicine Office of Research

713-798-6970 irb@bcm.edu

Principal Investigator:

Megan O'Brien, MD

Baylor - Christus Children's - Westover Hills

Recruiting

San Antonio, Texas, United States, 78251

Contacts

Baylor College of Medicine Office of Research

713-798-6970 irb@bcm.edu

Principal Investigator:

Megan O'Brien

Baylor - Christus Children's - Stone Oak

Recruiting

San Antonio, Texas, United States, 78258

Contacts

Baylor College of Medicine Office of Research

713-798-6970 irb@bcm.edu

Principal Investigator:

Megan O'Brien

The University of Vermont Children's Hospital

Recruiting

Burlington, Vermont, United States, 05401

Contacts

Iris Toedt-Pingel, MD

iris.toedt-pingel@uvmhealth.org

UVA Children's Hospital

Recruiting

Charlottesville, Virginia, United States, 22903

Contacts

Michelle Adu-Darko, MD

maa7j@hscmail.mcc.virginia.edu

Seattle Children's Hospital

Recruiting

Seattle, Washington, United States, 98105

Contacts

Alisyn Franetich

206-884-2910 alisyn.franetich@seattlechildrens.org

Principal Investigator:

Taylor Sawyer, MD

University of Washington Medical Center

Recruiting

Seattle, Washington, United States, 98195

Contacts

Alisyn Franetich

206-884-2910 alisyn.franetich@seattlechildrens.org

Principal Investigator:

Taylor Sawyer, MD

University of Wisconsin - UnityPoint Meriter

Recruiting

Madison, Wisconsin, United States, 53715

Contacts

Liz Michaels

608-417-6411 liz.michaels@unitypoint.org

Principal Investigator:

Patrick Peebles

American Family Children's Hospital - University of Wisconsin

Recruiting

Madison, Wisconsin, United States, 53792

Medical College of Wisconsin

Recruiting

Milwaukee, Wisconsin, United States, 53226

University of Wisconsin - American Family Children's Hospital

Recruiting

Shorewood Hills, Wisconsin, United States, 53792

Contacts

The University of Wisconsin IRB

608-263-2362 pjpeebles@wisc.edu

Principal Investigator:

Patrick Peebles

Foothills Medical Centre

Recruiting

Calgary, Alberta, Canada, T2N 2T9

Contacts

403-944-1110

Principal Investigator:

Ayman About Mehrem

Alberta Children's Hospital

Recruiting

Calgary, Alberta, Canada, T3B 6A9

Contacts

Simon Parsons, MD

simon.Parsons@albertahealthservices.ca

British Columbia Children's Hospital

Recruiting

Vancouver, British Columbia, Canada, V6H 3V4

Contacts

Gordon Krahn, MD

gkrahn@cw.bc.ca

CHU Sainte-Justine

Recruiting

Montreal, Quebec, Canada, H3T 1C4

Contacts

Guillaume Emeriaud, MD

guillaume.emeriaud@umontreal.ca

CHU Sainte-Justine

Recruiting

Montreal, Quebec, Canada, QC H3T 1C5

The University of Manitoba

Recruiting

Winnipeg, Canada, B R3T 2N2

Contacts

(800) 432-1960

Principal Investigator:

Michael Narvey

More Information

Sponsor

Children's Hospital of Philadelphia

Last update posted

Jan 9, 2026

Last verified

Jan, 2026

Keywords

Intubation
Advanced airway intervention
Intensive care unit

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Children's Hospital of Philadelphia on 2026-01-09.