Recruiting

Observational Study

Sponsor:

University Health Network, Toronto

Code:

NCT02495337

Conditions

Esophageal Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Tissue Collection

Study Details

Brief summary:

This proposed collection of primary tumor cells lines will benefit esophageal cancer research within the University Health Network. This collection of gastro-esophageal tumor samples will be used to grow primary tumor cell lines, which will provide researchers with ready samples of various gastro-esophageal cancers. This will help to address the issue of access to these cell lines due to the limited number of patients with gastro-esophageal tumors, and high rates of contamination.

Conditions

Esophageal Cancer

Study ID

NCT02495337

Start date

May, 2015

Status verified date

May, 2025

Completion date

Dec, 2030

Anticipated

Primary completion date

Dec, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients with esophagogastric cancer and/or GERD +/- Barrett's esophagus who will undergo surgery and/or EGD as standard of care.

Exclusion Criteria:

  • Patients who are not well enough to undergo surgery or EGD as standard of care.

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Arms

TIssue Collection

Only one arm will be used to collect tissue from Esophageal Adenocarcinoma

Interventions

Tissue Collection

Primary outcome measure

  • Effectively culture, proliferate, and store primary gastro-esophageal cell lines in order to create a bank of primary esophageal / gastric cancers for research purposes [ Time Frame: Ongoing ]

Central Contacts and Locations

Central contacts

Frances Allison

416-340-5446Frances.Allison@uhn.ca

Locations

University Health Network: Toronto General Hospital

Recruiting

Toronto, Ontario, Canada, M5G 2C4

Contacts

Frances Allison

416-340-5446Frances.Allison@uhn.ca

Principal Investigator:

Gail Darling, MD

More Information

Sponsor

University Health Network, Toronto

Last update posted

May 14, 2025

Last verified

May, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University Health Network, Toronto on 2025-05-14.