Recruiting

Prostate Cancer

Sponsor:

Sir Mortimer B. Davis - Jewish General Hospital

Code:

NCT02573636

Conditions

Prostate Cancer

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The objective of the study is to evaluate the predictive value of TMPRSS2-ERG gene fusion and PTEN in patients with high risk prostate cancer treated with first line LHRH agonist after biochemical failure.

Conditions

Prostate Cancer

Study ID

NCT02573636

Start date

Mar, 2016

Status verified date

Dec, 2024

Completion date

Mar, 2027

Anticipated

Primary completion date

Nov, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • T3a +
  • PSA > 20
  • Gleason 8 or higher
  • Karnofsky performance status ≥ 70.
  • Signed study-specific informed consent

Exclusion Criteria:

-

Study Design

Enrollment

208 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Number of patients with biochemical failure showing coexistence of PTEN and TMPRSS2-ERG gene fusion. [ Time Frame: recruitment over 4 years ]

Central Contacts and Locations

Central contacts

Ashley Feng, M.Sc.

514-340-8222yanqi.feng.ccomtl@ssss.gouv.qc.ca

Locations

CIUSSS du Saguenay-Lac-St-Jean/CSSS de Chicoutimi

Recruiting

Chicoutimi, Quebec, Canada, G7H 5H6

CISSS de la Montérégie-Centre - Hôpital Charles-LeMoyne

Recruiting

Greenfield Park, Quebec, Canada, J4V 2H1

CISSS de Laval - Hôpital de la Cité-de-la-santé de Laval

Recruiting

Laval, Quebec, Canada, H7M 3L9

CIUSSS de l'Est-de-l'Île-de-Montréal - Hôpital Maisonneuve-Rosemont

Recruiting

Montreal, Quebec, Canada, H1T 2M4

Jewish General Hospital, McGill University

Recruiting

Montreal, Quebec, Canada, H3T 1E2

Contacts

Ashley Feng, M.Sc.

514-340-8222yanqi.feng.ccomtl@ssss.gouv.qc.ca

MUHC - Cedars Cancer Center

Recruiting

Montreal, Quebec, Canada, H4A 3J1

CIUSSS de la Mauricie-et-du-centre-du Quebec - Centre hospitalier régional de Trois-Rivières

Recruiting

Trois-Rivières, Quebec, Canada, G8Z 3R9

CHU - L'Hôtel-Dieu de Québec

Recruiting

Quebec, Canada, G1R 2J6

More Information

Sponsor

Sir Mortimer B. Davis - Jewish General Hospital

Last update posted

Dec 4, 2024

Last verified

Dec, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Sir Mortimer B. Davis - Jewish General Hospital on 2024-12-04.