Recruiting

Observational Study

Sponsor:

Unity Health Toronto

Code:

NCT02623192

Conditions

Acute Respiratory Distress Syndrome

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Interventions

Patients who have performed the ARDS pulmonary function test

Study Details

Brief summary:

This registry was proposed to investigate the epidemiology of respiratory mechanics in patients with ARDS through collecting data from a QI project which was constituted with systematic assessments of respiratory mechanics and gas exchange.

Conditions

Acute Respiratory Distress Syndrome

Study ID

NCT02623192

Start date

Aug, 2014

Status verified date

Jul, 2017

Completion date

Aug, 2018

Anticipated

Primary completion date

Aug, 2018

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • All patients admitted to the Medical-Surgical ICU, Trauma-Neuro ICU, and Cardiovascular ICU who meet the Berlin definition of ARDS and receive invasive ventilation.

Exclusion Criteria:

  • Severe hemodynamic instability: > 30% variation of mean arterial pressure and/or heart rate (HR) in the last 2 hours or the need for a high dose of vasopressors (higher than 0.5 µg/kg/min of norepinephrine);
  • Patients who present with a known esophageal problem, active upper gastrointestinal bleeding, or any other contraindication for the insertion of a gastric tube.

Study Design

Enrollment

200 participants

Anticipated

Interventions and Outcome Measures

Arms

ARDS

Interventions

Patients who have performed the ARDS pulmonary function test

Primary outcome measure

  • Driving pressure (centimetre of water) [ Time Frame: One hour ]

Central Contacts and Locations

Central contacts

Laurent Brochard, MD

416-864-5686BrochardL@smh.ca

Locations

St. Michael's Hospital

Recruiting

Toronto, Ontario, Canada, M5B 1W8

Contacts

Laurent Brochard

brochardl@smh.ca

More Information

Sponsor

Unity Health Toronto

Last update posted

Jul 26, 2017

Last verified

Jul, 2017

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Unity Health Toronto on 2017-07-26.