Recruiting

Amino Acids & Exercise

Sponsor:

University of Western Ontario, Canada

Code:

NCT02630238

Conditions

Weight Loss

Obesity

Eligibility Criteria

Sex: Female

Age: 18 - 25

Healthy Volunteers: Accepted

Interventions

Branched-Chain Amino Acid Supplementation

Placebo

Exercise

Diet

Study Details

Brief summary:

This double blind placebo study will take place over an 8 week treatment period of diet and exercise. All participants (n=16), in two groups, will be placed on the same hypocaloric diet and exercise program. Participants will be matched into pairs based on body fat % and then assigned into a test group \& a placebo group. The placebo will be in the form of a powdered isoenergetic beverage with carbohydrate similar in taste \& appearance to the powder BCAA supplement that the test group will receive. The test group will be put on 0.342g/kg of BCAA per day, partially accounted for through their diet with the rest provided by a BCAA supplement. At baseline, 4 weeks and 8 weeks habitual 3 day food logs, waist to hip ratio and BodPod measures of body fat \& lean mass (both percentage \& absolute values) will be taken for all participants.

Conditions

Weight Loss

Obesity

Study ID

NCT02630238

Start date

Jan, 2016

Status verified date

Jan, 2016

Completion date

Apr, 2016

Anticipated

Primary completion date

Apr, 2016

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 25

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy, sedentary, overweight (BMI 25-29.9) females, between the ages of 18 - 25 years. Men will need to be measured in a separate study as there are likely gender differences and as this is an undergraduate student project there is insufficient time to assess both.

Exclusion Criteria:

  • Women who are; unhealthy, currently physically active, taking medications, have health conditions contraindicated participation in exercise, allergic to milk, pregnant, or breastfeeding will be excluded.

Study Design

Enrollment

16 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Interventions and Outcome Measures

Arms

experimental: Branched-Chain Amino Acid group

The branched-chain amino acid group will be on a hypocaloric diet, exercise and receive 0.342g/kg of BCAA per day, partially accounted for through their diet with the rest provided by a BCAA supplement

placebo comparator: Placebo Group

The placebo will be on a hypocaloric diet, exercise and receive isoenergetic beverage with carbohydrate instead of branched-chain amino acids

Interventions

Branched-Chain Amino Acid Supplementation

All participants will partake in the same diet \& exercise regime but this group will also be placed on a BCAA intake level of 0.342g/kg of BCAA per day

Placebo

All participants will partake in the same diet \& exercise regime but this group will receive an isocaloric placebo in form of carbohydrate solution

Exercise

Exercise will take place in a class based, circuit training setting run by a certified personal trainer composed of both aerobic and lifting exercises

Diet

Each participants will be placed on a daily energy deficit of 500 calories for the 8 week study period.

Primary outcome measure

  • Measuring changes in Lean Mass over 8 weeks at different time points [ Time Frame: 4 weeks & 8 weeks ]

Central Contacts and Locations

Central contacts

Peter Lemon, PhD, FACSM

19-661-2111plemon@uwo.ca

Alicia MacDougall

5192002901amacdou6@uwo.ca

Locations

Exercise Nutrition Research Laboratory, Western University

Recruiting

London, Ontario, Canada, N6A 3K7

Contacts

Peter Lemon, PhD

519 661 2111plemon@uwo.ca

Principal Investigator:

Peter Lemon, PhD

More Information

Sponsor

University of Western Ontario, Canada

Last update posted

Jan 20, 2016

Last verified

Jan, 2016

Keywords

  • Exercise
  • Amino Acids, Branched-Chain

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Western Ontario, Canada on 2016-01-20.