Recruiting

Observational Study

Sponsor:

University of Pennsylvania

Code:

NCT02753777

Conditions

Pemphigus Vulgaris

Pemphigus Foliaceus

Bullous Pemphigoid

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Questionnaires

Study Details

Brief summary:

Pemphigus and bullous pemphigoid (BP) are severe autoimmune blistering diseases (AIBD) that pose a critical need for new therapeutic approaches. Clinical trials in pemphigus and BP will require the availability of validated disease severity measures that can be used to define primary outcomes.

Conditions

Pemphigus Vulgaris

Pemphigus Foliaceus

Bullous Pemphigoid

Study ID

NCT02753777

Start date

Apr, 2016

Status verified date

Mar, 2026

Completion date

Jan 2, 2030

Anticipated

Primary completion date

Jan 2, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Gender/Age: Males or females above 18 years old
  • Diagnosis: pemphigus vulgaris, pemphigus foliaceus, bullous pemphigoid
  • Subjects able to give informed consent

Exclusion Criteria:

  • Patients who are under age 18 years.
  • Patients without pemphigus or pemphigoid diseases
  • Penn employees
  • Penn students
  • Cognitively impaired persons

Study Design

Enrollment

150 participants

Anticipated

Interventions and Outcome Measures

Interventions

Questionnaires

Primary outcome measure

  • Pemphigus Disease Area Index (PDAI) [ Time Frame: one year ]
  • Bullous Pemphigoid Disease Area Index (BPDAI) [ Time Frame: one year ]

Central Contacts and Locations

Central contacts

Victoria P Werth, MD

215-615-2940werth@pennmedicine.upenn.edu

Joyce Okawa, RN

215-615-2960Joyce.Okawa@pennmedicine.upenn.edu

Locations

Hospital of the University of Pennsylvania, Department of Dermatology

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Victoria P Werth, MD

215-615-2940werth@pennmedicine.upenn.edu

Joyce Okawa, RN

215-615-2940joyce.okawa@pennmedicine.upenn.edu

Principal Investigator:

Victoria P Werth, MD

Hospital of the University of Pennsylvania

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Victoria P Werth, MD

215-615-2940werth@pennmedicine.upenn.edu

University of Pennsylvania, Department of Dermatology

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Victoria P Werth, MD

215-615-2940werth@pennmedicine.upenn.edu

Principal Investigator:

Victoria P. Werth, MD

More Information

Sponsor

University of Pennsylvania

Last update posted

Mar 30, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by University of Pennsylvania on 2026-03-30.