Recruiting

Observational Study

Sponsor:

University of Pennsylvania

Code:

NCT02771496

Conditions

Osteochondritis Dissecans

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Interventions

Other: observational only- no intervention

Study Details

Brief summary:

The Cohort is a multi-site prospective data collection study that will enroll any patient with diagnosis of knee OCD (confirmed by a standard of care x-ray or MRI). Patients will be followed for up to the next 50 years of their lives to study courses of care, disease progression, treatment/surgical options/results, and specific sports-related outcomes in athletic patients. Subjects will complete quality of life surveys as part of the Cohort. Course of care will not be affected.

Conditions

Osteochondritis Dissecans

Study ID

NCT02771496

Start date

May 1, 2014

Status verified date

May, 2026

Completion date

Dec 1, 2074

Anticipated

Primary completion date

May 1, 2074

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosis of osteochondritis dissecans or focal articular cartilage defects as confirmed by x-ray or MRI

Exclusion Criteria:

  • Non-confirmed diagnosis (i.e. patient does not yet have imaging confirmation)

Study Design

Enrollment

3000 participants

Anticipated

Interventions and Outcome Measures

Arms

Patients with OCD

Patients with diagnosis of OCD as confirmed by x-ray or MRI. Surveys collected from patients at 2 years, 5 years, 10 years, and 25 years.

Interventions

Other: observational only- no intervention

Other: observational only- no intervention

Primary outcome measure

  • IKDC questionnaire [ Time Frame: baseline up to 50 years ]
  • PEDI-IKDC questionnaire [ Time Frame: baseline up to 50 years ]

Central Contacts and Locations

Central contacts

Mounika Ponakala, MS

6093343767mounika.ponakala@pennmedicine.upenn.edu

Locations

University of Pennsylvania

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Mounika Ponakala, BS

Mounika.Ponakala@Pennmedicine.upenn.edu

Principal Investigator:

James L Carey, MD

More Information

Sponsor

University of Pennsylvania

Last update posted

May 27, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by University of Pennsylvania on 2026-05-27.