Recruiting

Egf Receptor

Sponsor:

Douglas B. Sawyer

Code:

NCT02820233

Conditions

Heart Disease

Vascular Disease

Heart Failure

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

Conditions

Heart Disease

Vascular Disease

Heart Failure

Study ID

NCT02820233

Start date

Jun, 2015

Status verified date

Jul, 2024

Completion date

Jun, 2029

Anticipated

Primary completion date

Sep, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Clinical diagnosis of severe coronary artery disease scheduled to undergo coronary artery bypass surgery.

Exclusion Criteria:

  • less than 18 years of age
  • unwilling or unable to provide informed consent
  • known active myocarditis
  • hypertrophic cardiomyopathy
  • constrictive pericarditis or other significant pericardial disease
  • severe pulmonary hypertension
  • significant renal impairment (Cr > 2.5 mg/dL)
  • severe ventricular arrhythmias
  • pregnancy

Study Design

Enrollment

80 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • The number of highly proliferative clones isolated [ Time Frame: up to 14 days from isolation ]

Central Contacts and Locations

Central contacts

Joanne Burgess, RN

burgejs@mmc.org

Locations

Maine Medical Center

Recruiting

Portland, Maine, United States, 04102

Contacts

Joanne Burgess, RN

207-662-2414BURGEJS@mmc.org

More Information

Sponsor

Douglas B. Sawyer

Last update posted

Apr 3, 2025

Last verified

Jul, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Douglas B. Sawyer on 2025-04-03.