Recruiting

Biobank

Sponsor:

University of Colorado, Denver

Code:

NCT02864108

Conditions

Down Syndrome

Trisomy 21

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The Human Trisome Project will significantly increase the speed of Down syndrome research and the understanding of associated medical conditions. Its biobank will provide de-identified samples to research.

Conditions

Down Syndrome

Trisomy 21

Study ID

NCT02864108

Start date

Jul, 2016

Status verified date

Oct, 2025

Completion date

Jul, 2036

Anticipated

Primary completion date

Jul, 2036

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

Anyone 6 months to 89 years old who:

1. has Down syndrome (any type)
2. does not have Down syndrome

Exclusion Criteria:

1. Prisoners
2. Wards of the state

Study Design

Enrollment

2500 participants

Anticipated

Interventions and Outcome Measures

Arms

Those with trisomy 21

People aged 6 months to 89 years old who have some form of trisomy 21.

Controls

People aged 6 months to 89 years old who do not have trisomy 21. These persons can be related to someone with some form of trisomy 21 but do not have to be related.

Primary outcome measure

  • Number of Participants and Controls Enrolled in Biobank [ Time Frame: 5 years ]

Central Contacts and Locations

Central contacts

Angela Rachubinski, PhD

(303) 724-7366dsresearch@cuanschutz.edu

Constance Brecl, BA

dsresearch@cuanschutz.edu

Locations

Linda Crnic Institute for Down Syndrome at the University of Colorado Denver

Recruiting

Denver, Colorado, United States, 80045

Principal Investigator:

Joaquin Espinosa, PhD

More Information

Sponsor

University of Colorado, Denver

Last update posted

Oct 24, 2025

Last verified

Oct, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-11. This information was provided to ClinicalTrials.gov by University of Colorado, Denver on 2025-10-24. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.