Recruiting

Metabolic Responses

Sponsor:

Texas Christian University

Code:

NCT02966444

Conditions

Body Weight Changes

Eligibility Criteria

Sex: Female

Age: 18 - 40

Healthy Volunteers: Accepted

Interventions

MUFA-rich HF Meal

PUFA-rich HF Meal

SFA-rich HF Meal

Study Details

Brief summary:

This study evaluates the effects of dietary fatty acid composition from high fat meals on markers of hunger, satiety and metabolism.

Conditions

Body Weight Changes

Study ID

NCT02966444

Start date

Oct, 2016

Status verified date

Jul, 2018

Completion date

Jul, 2018

Anticipated

Primary completion date

Jul, 2018

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 40

Healthy Volunteers: Accepted

Inclusion Criteria:

  • BMI of >18.5-24.9kg/m2
  • Woman
  • 18-40yrs of age

Exclusion Criteria:

  • Evidence of weight loss or gain exceeding 5% of their body weight within the past 3 months.
  • Plans to lose weight or begin a weight loss program between initiation of study and final testing.
  • Plans to begin an exercise program or change current exercise routines between initiation of study and final testing.
  • Is on a medically prescribed diet
  • Does not consume breakfast regularly
  • Rate less than 80% of foods offered in the buffet at 50mm or more on the 100mm VAS as palatable
  • Medications that could influence appetite or sensory function
  • Reports of metabolic or endocrine disease, gastrointestinal disorders, or history of medical or surgical events that could affect fat digestion and hormone signaling.
  • Any chronic disease including type II diabetes, hypothyroidism, hyperthyroidism, cardiovascular disease, and cancer
  • Any supplements that a subject begins taking between initiation of study and final testing.
  • Anyone who is currently pregnant, lactating, or planning on becoming pregnant before the conclusion of this study.
  • Anyone who has allergies to any of the components of the liquid meals
  • Anyone who has donated blood in the last 20 days

Study Design

Enrollment

16 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: MUFA-rich HF Meal

High-fat meal rich in monounsaturated fatty acids

experimental: PUFA-rich HF Meal

High-fat meal rich in polyunsaturated fatty acids

experimental: SFA-rich HF Meal

High-fat meal rich in saturated fatty acids

Interventions

MUFA-rich HF Meal

PUFA-rich HF Meal

SFA-rich HF Meal

Primary outcome measure

  • Peptide-YY [ Time Frame: 18 months ]

Central Contacts and Locations

Central contacts

Jada L Stevenson, PhD

817-257-6310jada.stevenson@tcu.edu

Locations

Texas Christian University

Recruiting

Fort Worth, Texas, United States, 76102

Contacts

Jada L Stevenson, PhD

817-257-6310jada.stevenson@tcu.edu

More Information

Sponsor

Texas Christian University

Last update posted

Jul 26, 2018

Last verified

Jul, 2018

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Texas Christian University on 2018-07-26.