Recruiting

Observational Study

Sponsor:

University of Alabama at Birmingham

Code:

NCT03125655

Conditions

Psoriasis

Inflammation

Eligibility Criteria

Sex: All

Age: 19 - 70+

Healthy Volunteers: Accepted

Interventions

Inflammatory markers

Study Details

Brief summary:

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.

Conditions

Psoriasis

Inflammation

Study ID

NCT03125655

Start date

Apr 22, 2014

Status verified date

Apr, 2026

Completion date

Apr 28, 2028

Anticipated

Primary completion date

Apr 10, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 19 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Clinical diagnosis of psoriasis
  • Must be age 19 or older.
  • Must be Fitzpatrick skin type I, II, III, IV, V, VI.

Exclusion Criteria:

  • Subjects who do not have photosensitive disease and are not on photosensitizing medications.
  • Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy).
  • Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
  • Subjects who are pregnant.

Study Design

Enrollment

13 participants

Anticipated

Interventions and Outcome Measures

Interventions

Inflammatory markers

Primary outcome measure

  • Inflammatory genes [ Time Frame: 1 day ]

Central Contacts and Locations

Locations

The Kirklin Clinic

Recruiting

Birmingham, Alabama, United States, 35294

Contacts

Wendy Cantrell

205 502 9960wcantrell@uabmc.edu

More Information

Sponsor

University of Alabama at Birmingham

Last update posted

Apr 6, 2026

Last verified

Apr, 2026

Keywords

  • cytokines

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alabama at Birmingham on 2026-04-06.