Recruiting

Palmar Fasciectomy

Sponsor:

Mayo Clinic

Code:

NCT03155854

Conditions

Dupuytren Contracture

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Pretendinous cord excision

Division/manipulation of the cord

Study Details

Brief summary:

Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize recovery time and complications for patients. Some patients undergoing trigger finger surgery with a pre-existing Dupuytren's cord may develop a thickened surgical scar after surgery, which can cause discomfort, difficulty with moving or using, and other complications in the affected finger(s) or hand. The investigator is investigating a surgical technique to minimize these potential complications and scarring after surgery.

Subjects are being asked to take part in this research study because they have been diagnosed with trigger finger and pretendinous Dupuytren's cord and have decided to undergo surgery rather than try medical treatment.

Conditions

Dupuytren Contracture

Study ID

NCT03155854

Start date

Sep, 2016

Status verified date

Mar, 2026

Completion date

Dec, 2026

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Potential candidates for the study will be selected based upon clinical diagnosis of trigger finger with co-existing pretendinous cord. All potential subjects will have either failed non operative treatment or elected surgical treatment.

Exclusion Criteria:

  • <18 years of age

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Pretendinous cord excision

Patients will undergo either a targeted palmar fasciectomy procedure in which the involved Dupuytren's fascia will be excised

active comparator: Division/manipulation of the cord

patients will undergo either a targeted palmar fasciectomy procedure in which the involved Dupuytren's fascia will be incised.

Interventions

Pretendinous cord excision

The cord/palmar fascia will be excised during surgery.

Division/manipulation of the cord

The pretendinous cord will be divided and incised during surgery.

Primary outcome measure

  • Change in Scar Progression as measured by the Vancouver Scar Scale [ Time Frame: baseline, up to 1 year ]
  • Change in Scar Progression as measured by the Patient and Observer Scar Assessment Scale [ Time Frame: baseline, up to 1 year ]

Central Contacts and Locations

Central contacts

Sanjeev Kakar, MD

Kakar.Sanjeev@mayo.edu

Locations

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

More Information

Sponsor

Mayo Clinic

Last update posted

Mar 16, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-03-16.