Recruiting

SLT

Sponsor:

St. Joseph's Healthcare Hamilton

Code:

NCT03164941

Conditions

Glaucoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Selective Laser Trabeculoplasty

Study Details

Brief summary:

Selective Laser Trabeculoplasty (SLT) is a glaucoma treatment that has been shown to effectively lower intraocular pressure by increasing aqueous outflow through macrophage recruitment. There is evidence of increased drainage in the nasal quadrants of the eye. This study aims to compare whether there is a difference in the reduction of eye pressure when SLT is performed nasally and temporally.

Conditions

Glaucoma

Study ID

NCT03164941

Start date

Jul 1, 2017

Status verified date

May, 2017

Completion date

Dec 1, 2020

Anticipated

Primary completion date

Dec 1, 2019

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Diagnosis of open angle glaucoma, ocular hypertension, pigmentary dispersion syndrome and pseudoexfoliation syndrome
  • Participant must be over 18 years of age
  • IOP > 16mmHg on at least two consecutive occasions separated by one month
  • Two sighted eyes with visual acuity of 20/200 or better
  • Informed consent from patient

Exclusion Criteria:

  • Diagnosis of secondary OAG (aside from pigmentary and pseudoexfoliation glaucoma) or narrow angle glaucoma
  • Previous incisional glaucoma surgery
  • Incisional glaucoma surgery scheduled within 1 year of intervention
  • Corneal disease affecting visualization of anterior chamber of the eye
  • Treatment or plan to treat with topical or systemic steroids
  • Previous selective laser trabeculoplasty treatment

Study Design

Enrollment

84 participants

Anticipated

Interventions and Outcome Measures

Arms

Nasal SLT

This cohort will have 180 degree SLT completed on the nasal quadrants of the trabecular meshwork.

Temporal SLT

This cohort will have 180 degree SLT completed on the temporal quadrants of the trabecular meshwork.

Interventions

Selective Laser Trabeculoplasty

Laser treatment for glaucoma.

Primary outcome measure

  • Intraocular Pressure [ Time Frame: 1 year ]

Central Contacts and Locations

Locations

St Joseph's Healthcare Hamilton - King Campus

Recruiting

Hamilton, Ontario, Canada

Contacts

Sharan Bains, MD

905-522-1155bainss@mcmaster.ca

More Information

Sponsor

St. Joseph's Healthcare Hamilton

Last update posted

May 24, 2017

Last verified

May, 2017

Keywords

  • selective laser trabeculoplasty
  • practice
  • treatment
  • intraocular pressure

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by St. Joseph's Healthcare Hamilton on 2017-05-24.