Recruiting

Observational Study

Sponsor:

National Cancer Institute (NCI)

Code:

NCT03269578

Conditions

Neoplasms

Lymphoma

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Background:

People who join a study in the Developmental Therapeutics Clinic (DTC) have tests. These include blood draws and biopsies. Researchers collect data from these samples. Some people take part in more than one study at the DTC. At this time, data are connected only with one single study. Researchers want to access people s medical records. This will allow them to link the research data from all their studies they have or will take part in. Researchers also want to collect medical data about their diagnosis and treatment history. This will allow them to see how their cancer reacted to different drugs over time.

Objective:

To enter people into a master protocol to connect research sample and treatment data across DTC studies.

Eligibility:

People ages 18 and older who are being evaluated or treated for cancer in the DTC

Design:

Participants will allow researchers to look at all the data from their research samples. This includes those from their current, past, and any future NIH studies.

Participants will allow researchers to access some of their medical data. This includes age, diagnosis, treatment history, and response to treatment.

Participants will provide no new samples.

Conditions

Neoplasms

Lymphoma

Study ID

NCT03269578

Start date

Aug 28, 2017

Status verified date

May 19, 2026

Completion date

May 30, 2027

Anticipated

Primary completion date

May 23, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

  • INCLUSION CRITERIA:
  • Patients who are being evaluated and/or treated for cancer or benign tuumors in the Developmental Therapeutics Clinic at the NIH Clinical Center
  • Ability to understand and willingness to sign a written informed consent document indicating their willingness to have data from their tissue or biologic fluid research specimens and limited medial information used for research as outlined in this protocol and to allow protocol staff access to the CRIS database and their Medical Records Number (MRN).
  • Age greater than or equal to 18 years

ECLUSION CRITERIA:

None

Study Design

Enrollment

3000 participants

Anticipated

Interventions and Outcome Measures

Arms

1

Patients with cancer or benign tumors being treated on NCI/DTC studies

Primary outcome measure

  • Obtaining informed consent [ Time Frame: Time of enrollment ]

Central Contacts and Locations

Central contacts

Jennifer H Zlott

(240) 760-6046zlottjh@mail.nih.gov

Alice P Chen, M.D.

(240) 781-3320chenali@mail.nih.gov

Locations

National Institutes of Health Clinical Center

Recruiting

Bethesda, Maryland, United States, 20892

Contacts

For more information at the NIH Clinical Center contact National Cancer Institute Referral Office

888-624-1937

More Information

Sponsor

National Cancer Institute (NCI)

Last update posted

Sep 1, 2026

Last verified

May 19, 2026

Keywords

  • Pharmacodynamics
  • Tissue Collection
  • Tissue Biopsies
  • Biospecimen
  • Assay Development
  • Natural History

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by National Cancer Institute (NCI) on 2026-09-01.