Recruiting

Upper Expansion Appliances

Sponsor:

University of Alberta

Code:

NCT03286569

Conditions

Overbite (Excessive) Horizontal

Eligibility Criteria

Sex: All

Age: 9 - 11

Healthy Volunteers: Accepted

Interventions

Upper arch Wilson quadhelex appliance

Study Details

Brief summary:

Young children with backward positioned lower jaw/chin will be recruited to have an upper jaw expansion appliance. Previous research showed that the use of similar appliances can lead to lower jaw forward growth. 60 young children aged 9-11 will be recruited to have either active or non-active Wilson type upper arch expansion appliance. Patients will have special x-ray (Cone Beam computed tomography) before and after treatment (after 9 months) of starting the treatment. After participation, routine orthodontic treatment will be continued.

Conditions

Overbite (Excessive) Horizontal

Study ID

NCT03286569

Start date

Apr 1, 2019

Status verified date

Jan, 2026

Completion date

Feb 1, 2027

Anticipated

Primary completion date

Feb 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 9 - 11

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Class II skeletal due to lower jaw backward projection
2. Class II malocclusion
3. Early mixed dentition (all first permanent molars erupted, as well as all erupting upper and lower permanent incisors)

Exclusion Criteria:

1. Other orthodontic treatment provided
2. Growth problems (craniofacial syndromes, etc.)

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Active upper Wilson appliance

Active upper arch Wilson quadhelex appliance

placebo comparator: Non active upper expansion appliance

Non-Active upper arch Wilson quadhelex appliance

Interventions

Upper arch Wilson quadhelex appliance

Upper arch Wilson quadhelex appliance

Primary outcome measure

  • Lower jaw size [ Time Frame: 9 months ]
  • Lower jaw projection [ Time Frame: 9 months ]

Central Contacts and Locations

Central contacts

Dr. Tarek El-Bialy, PhD

780-492-2751telbialy@ualberta.ca

Rabia Njie, BDS

780-850-8752rnjie@ualberta.ca

Locations

University of Alberta

Recruiting

Edmonton, Alberta, Canada, T6G 2R3

Contacts

Tarek El-Bialy

telbialy@ualberta.ca

More Information

Sponsor

University of Alberta

Last update posted

Jan 7, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alberta on 2026-01-07.