Recruiting

Mixed Nuts

Sponsor:

San Diego State University

Code:

NCT03375866

Conditions

Satiety

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Accepted

Interventions

Pretzels

Mixed nuts

Study Details

Brief summary:

The first goal of the proposed study is to determine acute and long-term effects of mixed nuts (almonds, hazelnuts, pecans, pistachios, walnuts, and peanuts) on metabolic parameters and weight management. While numerous studies have shown the beneficial effects of nuts on promoting negative energy balance and weight loss, mechanistic studies exploring how the inclusion of nuts in the diet promotes a negative energy balance and weight loss have not been conducted. The second goal is to determine the mechanisms by which mixed nut consumption regulates of food intake and body weight.

Conditions

Satiety

Study ID

NCT03375866

Start date

Dec, 2016

Status verified date

Jan, 2026

Completion date

Dec, 2028

Anticipated

Primary completion date

Dec, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18-55 years old
  • BMI 27-40

Exclusion Criteria:

  • Smoker
  • Pregnant woman
  • Required dietary supplement use
  • Required medication of metabolic disorders
  • Allergy to nuts or gluten

Study Design

Enrollment

56 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

active comparator: Pretzels

experimental: Mixed nuts

Interventions

Pretzels

Subjects consume 240 kcal of pretzels daily for 16 weeks.

Mixed nuts

Subjects consume 240 kcal of mixed nuts daily for 16 weeks.

Primary outcome measure

  • Change of Satiety [ Time Frame: 0, 20, 40, 60, 90 and 120 minutes post snack consumption ]
  • Change of glucose level [ Time Frame: Baseline, 40 minutes post snack consumption, and 8 weeks and 16 weeks post daily consumption ]
  • Change of insulin level [ Time Frame: Baseline, 40 minutes post snack consumption, and 8 weeks and 16 weeks post daily consumption ]
  • Change of cholesterol levels [ Time Frame: 8 weeks and 16 weeks post daily consumption ]
  • Change of Lp(a) [ Time Frame: 8 weeks and 16 weeks post daily consumption ]

Central Contacts and Locations

Central contacts

Mee Young Hong

619-594-2392mhong2@mail.sdsu.edu

Locations

School of Exercise and Nutritional Sciences, SDSU

Recruiting

San Diego, California, United States, 92182-7251

Contacts

Mee Young Hong

619-594-2392mhong2@mail.sdsu.edu

More Information

Sponsor

San Diego State University

Last update posted

Jan 21, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by San Diego State University on 2026-01-21.