Bronchial ThermoplastyPhenotyping Asthma for Bronchial Thermoplasty

Inclusion Criteria:

1. Patient undergoing elective bronchial thermoplasty
2. Patient is between the ages of 18 and 60
3. Patient is able to give informed consent
4. Negative pregnancy test for all female of childbearing potential who are sexually active and not using contraception, are seeking to become pregnant, or who are nursing.
5. Nonsmoking (<5 pack year tobacco exposure)
6. No history of co-existing lung disease
7. Meet American Thoracic Society criteria for diagnosis of asthma with either/or

1. Bronchodilator response to albuterol (≥12% change in FEV1)
2. Positive methacholine bronchoprovocation (PC20 < 25 mg/ml)

Exclusion Criteria:

1. Patients who are pregnant.
2. Patient does not meet the requirements to undergo clinical bronchial thermoplasty, as determined by the treating physician