Recruiting

Ablative Therapy

Sponsor:

Weill Medical College of Cornell University

Code:

NCT03492424

Conditions

Prostate Cancer

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Interventions

cryotherapy

Study Details

Brief summary:

The purpose of this study is collect observational data regarding patterns of care and outcomes of focal therapies for prostate cancer, including but not limited to: high-intensity focused ultrasound (HIFU), cryotherapy, focal laser ablation, irreversible electroporation, photodynamic therapy, and brachytherapy.

Conditions

Prostate Cancer

Study ID

NCT03492424

Start date

Jan 2, 2018

Status verified date

Dec, 2025

Completion date

Sep 2, 2039

Anticipated

Primary completion date

Mar 2, 2032

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • >18 years of age
  • Undergoing focal therapy for primary or salvage treatment of prostate cancer, or
  • Have received prior focal therapy

Exclusion Criteria:

  • Clinically-evident metastatic disease
  • Unable to fill out an English-language questionnaire

Study Design

Enrollment

200 participants

Anticipated

Interventions and Outcome Measures

Arms

Focal therapy for prostate cancer

All men >18 years of age undergoing focal therapy for primary or salvage treatment of prostate cancer will be included. Men who had received prior focal therapy are also eligible for inclusion.

The purpose of this study is collect observational data regarding patterns of care and outcomes of focal therapies for prostate cancer, including but not limited to: high-intensity focused ultrasound (HIFU), cryotherapy, focal laser ablation, irreversible electroporation, photodynamic therapy, and brachytherapy.

Interventions

cryotherapy

Subjects will receive focal cryotherapy for treatment of prostate cancer

Primary outcome measure

  • Prostate biopsy Gleason grade [ Time Frame: 12 months ]

Central Contacts and Locations

Central contacts

Holly Kuczynsk, BS

646-962-7523hok4001@med.cornell.edu

Locations

Weill Cornell Medicine

Recruiting

New York, New York, United States, 10065

Contacts

Holly Kuczynski

646-962-7523hok4001@med.cornell.edu

Principal Investigator:

Tim McClure, M.D.

More Information

Sponsor

Weill Medical College of Cornell University

Last update posted

Dec 23, 2025

Last verified

Dec, 2025

Keywords

  • prostate cancer
  • cryotherapy
  • focal therapy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Weill Medical College of Cornell University on 2025-12-23.