Recruiting
Phase 1
Phase 2

Bupivacaine

Sponsor:

University of Tennessee

Code:

NCT03560362

Conditions

Pain, Postoperative

Lung Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Bupivacaine liposome

Bupivacaine / Epinephrine

Study Details

Brief summary:

Randomized trial of intraoperative intercostal block with bupivacaine with epinephrine compared to lipossomal extended release bupivacaine.

Conditions

Pain, Postoperative

Lung Cancer

Study ID

NCT03560362

Start date

Jul 9, 2015

Status verified date

Jun, 2018

Completion date

Oct 31, 2018

Anticipated

Primary completion date

Oct 31, 2018

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria: Patients who will be undergoing minimally invasive thoracic surgery

  • Patients who will be undergoing minimally invasive thoracic surgery

Exclusion Criteria:

  • Open surgery
  • Chronic use of narcotics
  • Use of pregabalin or similar
  • Significant liver or kidney dysfunction

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Bupivacaine with epinephrine

Patients will receive intraoperative intercostal nerve block with bupivacaine

experimental: Lipossomal extended release bupivacaine

Patients will receive intraoperative intercostal nerve block with lipossomal extended release bupivacaine

Interventions

Bupivacaine liposome

Bupivacaine / Epinephrine

Primary outcome measure

  • Postoperative pain [ Time Frame: 3-5 days post op ]

Central Contacts and Locations

Central contacts

Benny Weksler, MD

901-448-2918bweksler@uthsc.edu

Suzie Glass, RN

901-448-2918Suzie.Glass@mlh.org

Locations

Methodist University Hospital

Recruiting

Memphis, Tennessee, United States, 38104

Contacts

Benny Weksler

901-448-2918bweksler@uthsc.edu

More Information

Sponsor

University of Tennessee

Last update posted

Jun 20, 2018

Last verified

Jun, 2018

Keywords

  • bupivacaine
  • lipossomal extended release bupivacaine
  • Intercostal nerve block
  • thoracic surgery
  • minimally invasive surgery

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Tennessee on 2018-06-20.