Recruiting

MBLT

Sponsor:

Portland VA Medical Center

Code:

NCT03578003

Conditions

Brain Injuries, Traumatic

Post-traumatic Stress Disorder

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Morning Bright Light Therapy

Study Details

Brief summary:

One of the principal complicating factors associated with traumatic brain injury (TBI) is sleep-wake disturbances (e.g., insomnia, excessive daytime sleepiness, and circadian rhythm sleep disorders). Morning bright light therapy (MBLT) has been shown to improve sleep quality in a variety of conditions, but little has been done investigating the utility of MBLT in improving sleep in Veterans with TBI. This proposal aims to determine the effect of MBLT on sleep quality in Veterans with TBI. Veterans with and without TBI will be recruited from the VA Portland Health Care System. Baseline questionnaires and 7 days of actigraphy will be collected prior to engaging in 60 minutes of MBLT daily for 4 weeks, during which actigraphy will also be collected continuously. Post-MBLT questionnaire data will be collected, and follow-up questionnaire data will be collected at 3 months post-MBLT.

Conditions

Brain Injuries, Traumatic

Post-traumatic Stress Disorder

Study ID

NCT03578003

Start date

Aug 2, 2017

Status verified date

Nov, 2025

Completion date

Dec 1, 2026

Anticipated

Primary completion date

Dec 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Veterans

Exclusion Criteria:

  • History of bipolar disorder
  • History of macular degeneration
  • Non-English speaking
  • Decisionally impaired
  • Currently using a light box

Study Design

Enrollment

200 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Morning Bright Light Therapy

Subjects who engage in morning bight light therapy

no intervention: Control

Subjects who do not engage in morning bright light therapy

Interventions

Morning Bright Light Therapy

60 minutes of bright light therapy (10,000 lux) received within 90 minutes of waking

Primary outcome measure

  • Change in Insomnia Severity Index (ISI) [ Time Frame: Baseline; after 4 weeks of intervention; and 2 months after the end of intervention ]

Central Contacts and Locations

Central contacts

Miranda M Lim, MD, PhD

503-220-8262lmir@ohsu.edu

Jonathan E Elliott, PhD

503-220-8262elliojon@ohsu.edu

Locations

VA Portland Health Care System

Recruiting

Portand, Oregon, United States, 97239

Contacts

Miranda M Lim, MD, PhD

503-220-8262lmir@ohsu.edu

More Information

Sponsor

Portland VA Medical Center

Last update posted

Nov 14, 2025

Last verified

Nov, 2025

Keywords

  • Sleep
  • Bright Light

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Portland VA Medical Center on 2025-11-14.