Recruiting

Exercise Strategy

Sponsor:

Nova Scotia Health Authority

Code:

NCT03599843

Conditions

Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Exercise

Study Details

Brief summary:

Cancer continues to have the dubious honor of being the leading cause of premature mortality in Canada. The good news is, advances in early detection and cancer treatments are extending the lives of those diagnosed with the disease. However, as more people are living longer, the impact of the therapies used to treat the disease are becoming increasingly apparent. Ranging from the physiological to psychological, cancer survivors are often confronted with substantial, disabling, and life-threatening consequences. The benefits of physical activity (all movement) and exercise more specifically have long been established as a means of prevention and treatment of chronic disease. Several recent reviews and meta-analyses have demonstrated that exercise is a safe and effective means of preventing and improving a multitude of physical and psychological treatment and disease-related sequelae across the cancer trajectory. For example, we know that cancer survivors who exercise not only have a reduced risk of disease recurrence and cancer mortality, but also have reduced acute/late effects of their cancer and/or its treatment such as anxiety, depression, and cancer-related pain. Regrettably, despite our substantial knowledge base, the majority of cancer survivors are not sufficiently active to realize these benefits over the long-term. Moreover, even with the development of evidence-based guidelines, exercise has not yet been widely implemented as a standard of care in the oncology setting largely due to a lack of resources, exercise expertise, and awareness of benefits. Continuing to provide cancer care with little guidance and understanding of the benefits of exercise places cancer survivors at an increased risk for recurrence, late effects, and/or onset of additional co-morbidities, and premature mortality. Therefore, it is important to consider best practices that will optimize and improve quality of survival. Building on the ongoing work of our Alberta-based colleagues and the Alberta Cancer Exercise (ACE) Program (an evidence-based clinic-to-community cancer exercise model), Activating Cancer Communities through an Exercise Strategy for Survivors (ACCESS) is designed to bridge the gap between research and practice and in doing so, lessen the impact of a cancer diagnosis and its treatment(s) on the physical and psychological well-being of cancer survivors.

Conditions

Cancer

Study ID

NCT03599843

Start date

Sep 1, 2018

Status verified date

Feb, 2025

Completion date

Dec 31, 2025

Anticipated

Primary completion date

Dec 31, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Have a diagnosis of cancer;
  • Be 18+ years;
  • Be pre-treatment, receiving active treatment, or have received cancer treatment within the past 5 years or have a late presenting/ongoing side-effects related to the cancer diagnosis;
  • Be able to participate in mild levels of physical activity (at a minimum);
  • Be willing to attend a 12-week exercise program in Halifax;
  • Be able to provide informed written consent in English.

Exclusion Criteria:

- Less than 18 years of age.

Study Design

Enrollment

100 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: ACCESS

Individuals that consent to the study will be assigned to a 12-week exercise program (ACCESS)

Interventions

Exercise

Participants will complete a 12 week exercise session that will be comprised of aerobic and/or resistance and/or flexibility training.

Primary outcome measure

  • Physiological Outcome - resting heart rate [ Time Frame: 12 weeks ]
  • Physiological outcome - blood pressure [ Time Frame: 12 weeks ]
  • Physiological outcome - 6 minute walk test (6MWT) [ Time Frame: 12 weeks ]
  • Physiological Outcome - handgrip [ Time Frame: 12 weeks ]
  • Physiological outcome - timed sit-to-stand [ Time Frame: 12 weeks ]
  • Physiological Outcome - one legged stance/balance [ Time Frame: 12 weeks ]
  • Physiological Outcome - sit-and-reach [ Time Frame: 12 weeks ]
  • Physiological Outcome - shoulder flexibility [ Time Frame: 12 weeks ]
  • Daily steps [ Time Frame: 12 weeks ]
  • Functional Assessment of Cancer therapy General (FACT-G) [ Time Frame: 12 weeks ]
  • Physical Activity Behaviour [ Time Frame: 12 weeks ]
  • Sleep Quality [ Time Frame: 12 weeks ]
  • Depression Anxiety Stress Scales (DASS) [ Time Frame: 12 weeks ]
  • Fatigue [ Time Frame: 12-weeks ]

Central Contacts and Locations

Central contacts

Scott A Grandy, PhD

902-494-4303grandy@dal.ca

Locations

QEII Health Sciences Centre (Dickson Bldg)

Recruiting

Halifax, Nova Scotia, Canada, B3H 2Y9

Contacts

More Information

Sponsor

Nova Scotia Health Authority

Last update posted

Feb 17, 2025

Last verified

Feb, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Nova Scotia Health Authority on 2025-02-17.