Recruiting

Observational Study

Sponsor:

University of Louisville

Code:

NCT03670524

Conditions

Cardiovascular Diseases

Metabolic Health

Eligibility Criteria

Sex: All

Age: 30 - 70

Healthy Volunteers: Accepted

Interventions

Greenness as a therapeutic intervention

Study Details

Brief summary:

The purpose of this study is to examine how the environment and neighborhood characteristics affects the health of the area residents. The study will help determine how changing neighborhood characteristics, such as green space, affect heart health, risk factors for other diseases, sense of well- being or neighborhood cohesion.

Conditions

Cardiovascular Diseases

Metabolic Health

Study ID

NCT03670524

Start date

May 3, 2018

Status verified date

Feb, 2026

Completion date

Oct 30, 2028

Anticipated

Primary completion date

Oct 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 30 - 70

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 30-70 years of age.
  • Live within the targeted study location

Exclusion Criteria:

  • Unwilling or unable to provide consent.
  • HIV/AIDS, active treatment for cancer, active bleeding including wounds.
  • Body weight less than 100 pounds or BMI>40.
  • Prisoners and other vulnerable populations.
  • Anyone that PI thinks is unsafe to participate in study.

Study Design

Enrollment

835 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Targeted neighborhoods for Greenness

Using greenness as a therapeutic intervention, we will plant shrubs, grasses, young and mature trees (40-50 ft in height), so that we can evaluate changes in health and pollution, 2 years after planting.

no intervention: Control Group

No intervention

Interventions

Greenness as a therapeutic intervention

Greenness to be used as a therapeutic intervention

Primary outcome measure

  • Pulse Wave Analysis. Assess change from baseline arterial stiffness measurement and 2 year followup. [ Time Frame: Baseline and 2 year followup ]

Central Contacts and Locations

Central contacts

Jackie Research Coordinator, MS

502-852-6167jacqueline.gallagher@louisville.edu

Locations

University of Louisville

Recruiting

Louisville, Kentucky, United States, 40202

Contacts

Jackie Gallagher, MS

502-852-6167jacqueline.gallagher@louisville.edu

Principal Investigator:

Rachel Keith, PhD

More Information

Sponsor

University of Louisville

Last update posted

Feb 10, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Louisville on 2026-02-10.