Recruiting

Lifestyle Changes

Sponsor:

VA Palo Alto Health Care System

Code:

NCT03701815

Conditions

Stroke

Eligibility Criteria

Sex: All

Age: 30 - 70+

Healthy Volunteers: Not accepted

Interventions

Wellness in Rehabilitation program

Study Details

Brief summary:

This is a pilot study to determine whether a lifestyle medicine intervention following stroke may increase levels of Brain-Derived Neurotrophic Factor (BDNF).

Conditions

Stroke

Study ID

NCT03701815

Start date

Jan 19, 2018

Status verified date

Oct, 2018

Completion date

Feb 28, 2019

Anticipated

Primary completion date

Jan 11, 2019

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 30 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • History of prior stroke (ischemic or hemorrhagic) or transient ischemic attack
  • Ability to ambulate at least 10 feet with minimal to moderate assistance
  • Ability to travel to intervention site on a weekly basis.

Exclusion Criteria:

  • Cerebral aneurysm
  • Concurrent pregnancy
  • Serious terminal illnesses (e.g. end stage renal disease, heart failure (class IV), cirrhosis (class C), metastatic cancer)
  • Any injury or illness preventing participation in regular aerobic exercise
  • Moderate-severe dementia or cognitive decline

Study Design

Enrollment

12 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Post-stroke

Patients will receive a 12-week lifestyle medicine program.

Interventions

Wellness in Rehabilitation program

The 12-week Wellness in Rehabilitation program includes weekly in-person meetings including aerobic exercise, nutrition/cooking training, stress management techniques, education, and group support. A health coach will facilitate continuation of healthy behaviors at home.

Primary outcome measure

  • BDNF level - Final [ Time Frame: Week 12 ]

Central Contacts and Locations

Central contacts

Jeffrey Krauss, MD

6504935000jkrauss@stanford.edu

Windy McNerney, PhD

6504935000windymc@stanford.edu

Locations

VA Palo Alto Health Care System

Recruiting

Palo Alto, California, United States, 94304

Contacts

Jeffrey Krauss, MD

650-493-5000jeffrey.krauss@va.gov

More Information

Sponsor

VA Palo Alto Health Care System

Last update posted

Oct 10, 2018

Last verified

Oct, 2018

Keywords

  • brain-derived neurotrophic factor
  • exercise
  • BDNF
  • lifestyle medicine

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by VA Palo Alto Health Care System on 2018-10-10.