Recruiting

SPECT vs. xSPECT

Sponsor:

Carilion Clinic

Code:

NCT03702790

Conditions

Back Pain

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

SPECT-CT is evolving into an integral part of patient management in those having back pain. It can supplement other types of imaging like MRI by providing physiologic information about the type and location of various disease processes. This information can help guide therapy to the most active sites of disease which MRI and CT cannot do as anatomic imaging modalities. The nuclear department has two cameras that are capable of performing SPECT-CT, an Optima manufactured by GE and a Symbia Intevo Bold manufactured by Siemens. The Optima uses the Volumetrix Evolution algorithm to reconstruct SPECT data that does not incorporate the CT data into these reconstructions. The Bold, on the other hand, has a proprietary reconstruction algorithm called xSPECT which does use the CT data to extract a zone map to better delineate tissue boundaries. In this study, the investigators hope to compare images using the standard and proprietary algorithms to determine if these provide equal or different levels of image interpretation confidence by the reader as well as changes in clinical management.

Conditions

Back Pain

Study ID

NCT03702790

Start date

Oct 10, 2018

Status verified date

Jan, 2020

Completion date

Dec, 2020

Anticipated

Primary completion date

Dec, 2020

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Poorly localized back pain in search for guided therapy

Exclusion Criteria:

  • Allergy to MDP, radioisotope used for the examination. Patient limitations may include claustrophobia or inability to complete scan due to pain

Study Design

Enrollment

30 participants

Anticipated

Interventions and Outcome Measures

Arms

Back pain SPECT evaluation

Patients with poorly localized back pain being imaged for clinical decision making

Primary outcome measure

  • Measure any change in management in patients with back pain based on results of two different SPECT reconstruction algorithms using a qualitative visual measure. [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Locations

Carilion Roanoke Memorial Hospital

Recruiting

Roanoke, Virginia, United States, 24014

Contacts

More Information

Sponsor

Carilion Clinic

Last update posted

Jan 22, 2020

Last verified

Jan, 2020

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Carilion Clinic on 2020-01-22.