Recruiting

Tai Chi

Sponsor:

University of Massachusetts, Boston

Code:

NCT03705598

Conditions

Chronic Pain

Falls

Eligibility Criteria

Sex: All

Age: 65+

Healthy Volunteers: Not accepted

Interventions

Light physical exercise

Tai Chi

Study Details

Brief summary:

Accumulating evidence supports that more pain, whether measured by number of pain sites or pain severity, is associated with poorer cognitive function and mobility, and fall risk in older persons. Tai Chi which holistically integrates physical and cognitive functions offers the possibility not only of alleviating pain but also improving attention and mobility in the many older adults who have chronic multisite pain. This proposed full-size randomized controlled Tai Chi trial is a direct extension of the investigators' previous work examining chronic pain, attention demands, mobility and falls in the older population, and is built on the investigators' National Institute on Aging-supported Tai Chi feasibility and acceptability pilot studies among older adults with multisite pain and risk for falls. The goal of this single-blinded randomized controlled trial is to examine the effects of a 24-week Tai Chi intervention on chronic pain, cognition, mobility, fear of falling, and fall rate in older adults with multisite pain and at risk for falls. The results of this study will provide a foundation to establish the clinical significance of Tai Chi in the management of chronic multisite pain and to explore the mechanisms through which Tai Chi improves chronic pain symptoms and lowers fall rate in at-risk older adults.

Conditions

Chronic Pain

Falls

Study ID

NCT03705598

Start date

Oct 1, 2026

Status verified date

Oct, 2026

Completion date

Jul 31, 2030

Anticipated

Primary completion date

Apr 30, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 65+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. be 65 years or older
2. report chronic multisite (≥2 sites) musculoskeletal pain
3. have had 1 or more falls in the past year or current use of an assistive device (a cane or walker)
4. be able to walk 20 feet without help
5. be able to communicate in English

Exclusion Criteria:

1. actively engage in moderate to vigorous exercise for more than 40 min/week
2. practiced Tai Chi or other mind-body exercise within the past year, or practiced Tai Chi or other mind-body exercise regularly for at least 3 months within the past 5 years
3. have cognitive impairment consistent with dementia (Montreal Cognitive Assessment (MOCA) score < 18 after corrections),
4. have a diagnosis of a disease/condition that would interfere with their study participation (e.g., rheumatoid arthritis, stroke, Parkinson's disease, degenerative neuromuscular disease, unstable cardiac disease, Alzheimer's disease or other dementia, terminal disease)

Study Design

Enrollment

266 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

placebo comparator: Light physical exercise

Usual-pace walking, strength exercise, stretching exercise, and balance exercise.

active comparator: Tai Chi

Tai Chi walking drills and Yang-style Tai Chi 8 forms.

Interventions

Light physical exercise

One hour each session, two sessions each week, for 6 months. Each session will be structured into three 15-minute segments (including warm-up activities/balance exercise/walking, upper and lower body strength exercise/walking, and stretching exercise/balance exercise/walking, respectively), each ending with a short break to record the Borg Rating of Perceived Exertion (RPE), followed by a 5-minute break time or cool-down/wrap-up session. The session will be taught by a certified exercise physiologist and a research assistant.

Tai Chi

One hour each session, two sessions each week, for 6 months. Each session will be structured into three 15-minute segments (including warm-up activities/balance exercise/breathing exercise, Tai Chi walking drills, and Tai Chi 8-form, respectively), each ending with a short break to record the RPE, and followed by a 5-minute break or cool-down/wrap-up session. The session will be taught by an experienced Tai Chi instructor and a research assistant.

Primary outcome measure

  • Pain severity [ Time Frame: 6 months ]
  • Pain interference [ Time Frame: 6 months ]
  • Fear of falling [ Time Frame: 6 months ]
  • Rate of falls [ Time Frame: 12 months ]

Central Contacts and Locations

Central contacts

Tongjian You, PhD

6172875934Tongjian.you@umb.edu

Mekhala Rao, MPH

6172876297mekhala.rao@umb.edu

Locations

HELP Study Office and Lab

Recruiting

Boston, Massachusetts, United States, 02125

Contacts

Tongjian You, PhD

6172875934tongjian.you@umb.edu

Mekhala Rao, MPH

6172876297mekhala.rao@umb.edu

Principal Investigator:

Tongjian You, PhD

More Information

Sponsor

University of Massachusetts, Boston

Last update posted

Oct 7, 2026

Last verified

Oct, 2026

Keywords

  • Tai Chi
  • Chronic Pain
  • Falls
  • Older Adults

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-08. This information was provided to ClinicalTrials.gov by University of Massachusetts, Boston on 2026-10-07. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.