Recruiting

Cognitive Rehabilitation

Sponsor:

Rutgers, The State University of New Jersey

Code:

NCT03729713

Conditions

Multiple Sclerosis

Cognitive Impairment

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Interventions

Computerized cognitive rehabilitation

Sham placebo

Study Details

Brief summary:

This study examines a home-based computerized cognitive rehabilitation intervention in adults with multiple sclerosis compared to placebo (videogame). Patients are assessed through pre-and post neuropsychological testing.

Conditions

Multiple Sclerosis

Cognitive Impairment

Study ID

NCT03729713

Start date

Apr 21, 2021

Status verified date

Nov, 2022

Completion date

May, 2024

Anticipated

Primary completion date

May, 2023

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Diagnosis of multiple sclerosis with cognitive complaint

Exclusion Criteria:

1. Patients unwilling to participate
2. Patients who cannot attend NPT sessions
3. Patients with severe cognitive impairment
4. Non-English speaking patients (testing materials are in English)
5. Patients with intact neuropsychological functioning at baseline on testing

Study Design

Enrollment

80 participants

Anticipated

Allocation

Randomized

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Intervention

Computerized Cognitive Rehabilitation

sham comparator: Placebo

Video game

Interventions

Computerized cognitive rehabilitation

6 week course of cognitive rehabilitation focused on attention, learning, and memory

Sham placebo

an alternative home-based computer program not designed for cognitive remediation but of the same duration

Primary outcome measure

  • Cognitive Functioning [ Time Frame: 6 Months ]

Central Contacts and Locations

Central contacts

Vikram Bhise, MD

7322357875MSCogStudy@outlook.com

Locations

Robert Wood Johnson Medical School

Recruiting

New Brunswick, New Jersey, United States, 08091

Contacts

Vikram Bhise, MD

732-235-7875

Principal Investigator:

Vikram Bhise, MD

More Information

Sponsor

Rutgers, The State University of New Jersey

Last update posted

Nov 17, 2022

Last verified

Nov, 2022

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Rutgers, The State University of New Jersey on 2022-11-17.