Recruiting

Physical Activity

Sponsor:

Barbara Ann Karmanos Cancer Institute

Code:

NCT03750981

Conditions

Cancer Survivors

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

12 week pilot intervention study.

Study Details

Brief summary:

This study will introduce cancer survivors to cross-training with the expectation that the program proposed will ultimately result in superior improvements in functional performance, body composition and quality of life compared with the current American Cancer Society (ACS) guidelines for cancer survivors.

Conditions

Cancer Survivors

Study ID

NCT03750981

Start date

Nov 12, 2018

Status verified date

Nov, 2025

Completion date

Nov 30, 2028

Anticipated

Primary completion date

Nov 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Aged 18 years or older at time of program recruitment
  • Diagnosed with any cancer
  • Cleared from their physician to participate in the program (We assume that most patients will have completed treatment, however if a patient is currently under treatment, this should be their oncologist. If the patient is not currently undergoing treatment, this could be primary care physician or oncologist).
  • Available transportation to and from the facility on session days

Exclusion Criteria

  • Widely metastatic cancers to the brain or bone may be excluded.
  • Patients using mobility assistance devices may be excluded. Exclusionary criteria will be reviewed on a case-by-case basis and patients with these limitations may be included with approval from Dr. Beebe-Dimmer and the referring physician.

Study Design

Enrollment

500 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

other: A 12-week pilot intervention study introducing a high-intensi

Interventions

12 week pilot intervention study.

Participants will begin a 12-week high-intensity functional training program conducted at CrossFit® in the D, located in downtown Detroit, Northville Athletix in Northville and Five Lakes CrossFit® in Farmington Hills.

Primary outcome measure

  • Enrollment rates [ Time Frame: Baseline ]
  • Change in functional performance and variability in functional performance among adult cancer survivors enrolled in a high-intensity functional training program [ Time Frame: Baseline to 12 weeks ]
  • Change in functional performance and variability in functional performance among adult cancer survivors enrolled in a high-intensity functional training program [ Time Frame: Baseline to 12 weeks ]
  • Change in functional performance and variability in functional performance among adult cancer survivors enrolled in a high-intensity functional training program [ Time Frame: Baseline to 12 weeks ]
  • Change in self-reported health-related quality of life (HRQOL) and variability using the FACT questionnaire [ Time Frame: Baseline to 12 weeks ]
  • Change in Body Composition [ Time Frame: Baseline to 12 weeks ]
  • Change in Body Composition [ Time Frame: Baseline to 12 weeks ]
  • Change in Body Composition [ Time Frame: Baseline to 12 weeks ]
  • Change in Body Composition [ Time Frame: Baseline to 12 weeks ]
  • Change in Body Composition [ Time Frame: Baseline to 12 weeks ]
  • Change in Body Composition [ Time Frame: Baseline to 12 weeks ]
  • Change in Motivation [ Time Frame: Baseline to 12 weeks ]
  • Satisfaction with the Program [ Time Frame: 12 weeks ]
  • Program Adherence [ Time Frame: 12 weeks ]
  • Height [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

Jennifer B Beebe-Dimmer, MPH, PhD.

(313) 578-4209dimmerj@karmanos.org

Tara Baird, M.Ed.

(313) 578-4246bairdt@karmanos.org

Locations

Barbara Ann Karmanos Cancer Institute

Recruiting

Detroit, Michigan, United States, 48201

Contacts

Tara Baird

(313) 578-4246bairdt@karmanos.org

More Information

Sponsor

Barbara Ann Karmanos Cancer Institute

Last update posted

Nov 6, 2025

Last verified

Nov, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Barbara Ann Karmanos Cancer Institute on 2025-11-06.