Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Recruiting

Phase 2

Naive T-Cell DepletionNaive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Sponsor:

Fred Hutchinson Cancer Center

Code:

NCT03779854

Conditions

Acute Biphenotypic Leukemia

Acute Leukemia

Acute Leukemia of Ambiguous Lineage

Acute Lymphoblastic Leukemia

Acute Undifferentiated Leukemia

Eligibility Criteria

Sex: All

Age: 0 - 26

Healthy Volunteers: Accepted

Interventions

Total-Body Irradiation

Thiotepa

Fludarabine

Cyclophosphamide

Busulfan

Study Details

Eligibility Criteria

Study Design

Interventions and Outcome Measures

Central Contacts and Locations

More Information

Trial information was received from ClinicalTrials.gov and was last updated on 2025-10-19. This information was provided to ClinicalTrials.gov by Fred Hutchinson Cancer Center on 2025-10-15.