Recruiting

Observational Study

Sponsor:

University of Texas Southwestern Medical Center

Code:

NCT03811808

Conditions

Multiple System Atrophy (MSA)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This is a prospective cohort study to examine the disease burden of multiple system atrophy and the impact of multidisciplinary care on quality of life and caregiver burden. Data will be collected through valid rating scales completed by patients and caregivers at home or in the MSA clinic.

Conditions

Multiple System Atrophy (MSA)

Study ID

NCT03811808

Start date

Mar, 2016

Status verified date

May, 2026

Completion date

Mar, 2028

Anticipated

Primary completion date

Mar, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Subject must be a patient in the UT Southwestern MSA clinic and be able to attend the multidisciplinary clinic every 4 months
  • Patients with possible or probable MSA based on established criteria
  • Subjects must be 18 years or older

Exclusion Criteria:

  • Patients that are unable to give consent
  • Minor patients (younger than age 18)
  • Non-English speaking patients
  • Subjects that are diagnosed with dementia

Study Design

Enrollment

200 participants

Anticipated

Interventions and Outcome Measures

Arms

MSA patients

patients diagnosed with possible or probable multiple system atrophy

Primary outcome measure

  • Multiple System Atrophy-Quality of Life (MSA-QoL) [ Time Frame: at 5 year evaluation ]

Central Contacts and Locations

Central contacts

Amy Conger

214-648-0214Amy.Conger@UTSouthwestern.edu

Steve Hopkins, CCRC

214-648-9275Steve.Hopkins@UTSouthwestern.edu

Locations

UT Southwestern Medical Center

Recruiting

Dallas, Texas, United States, 75390

Contacts

Amy Conger

214-648-0214Amy.Conger@UTSouthwestern.edu

Steve Hopkins, CCRP

214-648-9275Steve.Hopkins@UTSouthwestern.edu

Principal Investigator:

Steven Vernino, MD

More Information

Sponsor

University of Texas Southwestern Medical Center

Last update posted

May 22, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Texas Southwestern Medical Center on 2026-05-22.