Recruiting
Phase 2
Phase 3

TAP Blocks vs. IV Lidocaine

Sponsor:

Benaroya Research Institute

Code:

NCT03843879

Conditions

Postoperative Pain

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Transversus Abdominis Plane Block

Intravenous Lidocaine

Study Details

Brief summary:

This study will compare continuous intravenous lidocaine against single-injection transversus abdominis plane (TAP) block as a modality for postoperative analgesia in kidney transplant surgery.

Conditions

Postoperative Pain

Study ID

NCT03843879

Start date

Apr 1, 2019

Status verified date

Jul, 2019

Completion date

Sep 1, 2021

Anticipated

Primary completion date

Mar 1, 2021

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Kidney transplant recipient
  • >18 years old
  • Consent to participate

Exclusion Criteria:

  • <18 years old
  • Refusal to participate
  • Chronic opioid use
  • Seizure disorder
  • Allergy to local anesthestics
  • Severe hepatic disease

Study Design

Enrollment

124 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: TAP Block

Single-injection transversus abdominis plane block

active comparator: IV Lidocaine

Continuous intravenous lidocaine infusion

Interventions

Transversus Abdominis Plane Block

Single-injection transversus abdominis plane block with 30 mL of 0.25% Bupivacaine with 1:400,000 epinephrine

Intravenous Lidocaine

Continuous intravenous lidocaine infusion

Primary outcome measure

  • Opioid Consumption [ Time Frame: 0-24 Hours ]

Central Contacts and Locations

Central contacts

Neil A Hanson, MD

206-223-6980neil.hanson@virginiamason.org

Wyndam M Strodtbeck, MD

206-223-6980wyndam.strodtbeck@virginiamason.org

Locations

Virginia Mason Medical Center

Recruiting

Seattle, Washington, United States, 98101

Contacts

Neil A Hanson, MD

neil.hanson@virginiamason.org

Wyndam M Strodtbeck, MD

wyndam.strodtbeck@virginiamason.org

More Information

Sponsor

Benaroya Research Institute

Last update posted

Jul 17, 2019

Last verified

Jul, 2019

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Benaroya Research Institute on 2019-07-17.