Recruiting

Tourette Syndrome

Sponsor:

Vanderbilt University Medical Center

Code:

NCT03851484

Conditions

Tourette Syndrome

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Patients with tics will be asked to complete a series of validated questionnaires (in electronic and/or paper format) regarding symptoms and conditions often associated with Tourette syndrome, including premonitory urges, sensory experiences, inattention, obsessive-compulsive tendencies, anxiety, and depression. Participants will also be asked to complete a quality of life assessment. This series of questionnaires will be administered annually.

Conditions

Tourette Syndrome

Study ID

NCT03851484

Start date

Apr 17, 2019

Status verified date

Mar, 2026

Completion date

Dec 31, 2028

Anticipated

Primary completion date

Mar 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion criteria:

  • 18 years of age or older
  • Ability to provide informed consent and answer self-report questionnaires independently in English
  • Diagnosis of Tourette syndrome (TS), chronic motor tic disorder, or chronic vocal tic disorder

Exclusion criteria:

  • History of psychotic disorder
  • History of significant neurologic disorder (e.g., stroke) other than TS or another chronic tic disorder

Study Design

Enrollment

214 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Baseline Sensory Perception Quotient score, short form [ Time Frame: Initial assessment at enrollment (time zero) ]
  • Change in Sensory Perception Quotient score, short form at 1 year [ Time Frame: 1 year ]
  • Change in Sensory Perception Quotient score, short form at 2 years [ Time Frame: 2 years ]

Central Contacts and Locations

Central contacts

Michelle Eckland, BS

615-875-7394michelle.r.eckland.1@vumc.org

Locations

Vanderbilt University Medical Center

Recruiting

Nashville, Tennessee, United States, 37232

Contacts

Michelle Eckland, BS

+1 (615)875-7394michelle.r.eckland.1@vumc.org

Principal Investigator:

David Isaacs, MD, MPH

More Information

Sponsor

Vanderbilt University Medical Center

Last update posted

Mar 13, 2026

Last verified

Mar, 2026

Keywords

  • Tourette syndrome
  • premonitory urge
  • sensory dysregulation
  • hypersensitivity

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Vanderbilt University Medical Center on 2026-03-13.