Recruiting

Sepsis Triage

Sponsor:

Hamilton Health Sciences Corporation

Code:

NCT03870789

Conditions

Sepsis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Given the implementation of the Hamilton Early Warning Score (HEWS) and the use of capnography by paramedics, this study will involve a large multi-site retrospective evaluation (before vs after implementation) of the HEWS score and comparison of the HEWS to systemic inflammatory response syndrome (SIRS), quick Sepsis Related Organ failure Assessment (qSOFA) and Modified Early Warning Score (MEWS) when applied retrospectively for the identification of sepsis in the prehospital setting.

Conditions

Sepsis

Study ID

NCT03870789

Start date

Dec 11, 2016

Status verified date

Mar, 2019

Completion date

Dec 31, 2019

Anticipated

Primary completion date

May 1, 2019

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Any patient to which paramedics apply the Hamilton Early Warning Score or patients who arrive to the Emergency Department (ED) by ambulance without a pre-alert and meet the definition of sepsis in the ED will also be included, and patient is ≥ 18 years

Exclusion Criteria:

Patient is an inter-facility transfer, or patients with absent vital signs are absent, or death before blood can be drawn in the Emergency Department, or the patient fits the criteria for another prehospital alert (ST-elevation myocardial infarction, cerebrovascular vascular accident, or trauma)

Study Design

Enrollment

400 participants

Anticipated

Interventions and Outcome Measures

Arms

Retrospective

The Investigators will examine data from 1-year prior to paramedic implementation of the Hamilton Early Warning Score tool.

Prospective

The Investigators will examine data from 1-year after paramedic implementation of the Hamilton Early Warning Score tool.

Primary outcome measure

  • Accuracy of HEWS [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Natasha Clayton, CRA, RA

905-521-2100clayton@mcmaster.ca

Locations

Centre for Paramedic Education and Research, Hamilton Health Sciences

Recruiting

Hamilton, Ontario, Canada, L8E 5E3

More Information

Sponsor

Hamilton Health Sciences Corporation

Last update posted

Mar 12, 2019

Last verified

Mar, 2019

Keywords

  • sepsis, septic shock, early warning scores, infecion

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Hamilton Health Sciences Corporation on 2019-03-12.