Recruiting

Exercise-induced Hypoalgesia

Sponsor:

Marquette University

Code:

NCT03871504

Conditions

Healthy Subjects

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Submaximal isometric exercise

Study Details

Brief summary:

The purpose of this study is to investigate the influence of baseline experimental pain sensitivity and expectation on the pain response following a single exercise session. Pain assessment will be done with different intensities of noxious stimuli. In addition, the expectation of how exercise impacts pain will be studied.

Conditions

Healthy Subjects

Study ID

NCT03871504

Start date

Nov 25, 2017

Status verified date

Mar, 2019

Completion date

Dec 30, 2022

Anticipated

Primary completion date

Dec 30, 2022

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy adults
  • English proficiency

Exclusion Criteria:

  • Acute pain condition
  • Chronic pain condition
  • Mental health disorder
  • Cardiovascular disease
  • Any chronic illness
  • Difficulty with physical exercise
  • Recent surgery
  • Pulmonary disease
  • Diabetes
  • Smoking
  • Raynaud disease
  • Claustrophobia

Study Design

Enrollment

250 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: submaximal isometric exercise.

submaximal isometric exercise will be performed.

no intervention: Quiet rest.

Subject will rest in seating position for a period that mimics the exercise time.

Interventions

Submaximal isometric exercise

The exercise is a submaximal isometric contraction

Primary outcome measure

  • The change from baseline of pain ratings during temporal summation of pressure pain assessment [ Time Frame: Before and immediately after exercise or quiet rest in session 1 and session 2 which will be on day 1 and day 7 of data collection. ]

Central Contacts and Locations

Central contacts

Marie Hoeger Bement, PT, PhD

414-288-6738mariehoeger.bement@marquette.edu

Locations

Marquette University

Recruiting

Milwaukee, Wisconsin, United States, 53201

More Information

Sponsor

Marquette University

Last update posted

Mar 12, 2019

Last verified

Mar, 2019

Keywords

  • exercise
  • hypoalgesia
  • pain
  • expectation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-25. This information was provided to ClinicalTrials.gov by Marquette University on 2019-03-12. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.