Recruiting

Hepatocellular Carcinoma

Sponsor:

The University of Texas Health Science Center at San Antonio

Code:

NCT03894917

Conditions

Carcinoma, Hepatocellular

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Comprehensive Geriatric Assessment (CGA)

Study Details

Brief summary:

This is an observational, prospective cohort study that will recruit a diverse sample of 84 participants with newly diagnosed with unresectable, advanced hepatocellular carcinoma (HCC) at the UT Health Cancer Center in San Antonio. This study uses geriatric assessment tools with participants 65 years and older and collects adverse events and exploratory markers of aging for all participants.

Conditions

Carcinoma, Hepatocellular

Study ID

NCT03894917

Start date

Sep 13, 2019

Status verified date

Jan, 2026

Completion date

Dec, 2027

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Histologically or radiographically (CT or MRI) confirmed newly diagnosed hepatocellular carcinoma.
  • Age 18 years and older.
  • Patients with advanced, unresectable HCC as determined by the treating physician.

Exclusion Criteria:

  • Patients with resectable HCC who are still candidates for locoregional therapy
  • Patients receiving prior systemic or locoregional therapy

Study Design

Enrollment

84 participants

Anticipated

Interventions and Outcome Measures

Arms

Group 1

Participants 65 years or older

Group 2

Participants less than 65 years

Interventions

Comprehensive Geriatric Assessment (CGA)

Assessments will be done for participants that are 65 years or older.

Primary outcome measure

  • Characterize the Change in disease and treatment patterns of advanced hepatocellular carcinoma (HCC) in older patients in the US. [ Time Frame: will be collected at time points: at screening, Month 1, Month 2, Month 4, Month 6, Month 8, Month 10 and Month 12. ]

Central Contacts and Locations

Central contacts

Maggie Tomasini, MPH

210-450-0507tomasinim@uthscsa.edu

Locations

Mays Cancer Center

Recruiting

San Antonio, Texas, United States, 78229

Contacts

Gina Alvarez, RN

210-450-5893alvarezg1@uthscsa.edu

More Information

Sponsor

The University of Texas Health Science Center at San Antonio

Last update posted

Jan 8, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by The University of Texas Health Science Center at San Antonio on 2026-01-08.