Recruiting

Cognition Enhancement

Sponsor:

Jeanne Townsend, PhD

Code:

NCT03900702

Conditions

Cognitive Enhancement

Aging

Eligibility Criteria

Sex: All

Age: 60 - 70+

Healthy Volunteers: Accepted

Interventions

Gaze-driven training games

Study Details

Brief summary:

This is a planning project with a clinical trial pilot to prepare for a larger fully powered clinical trial. Goals of this pilot project are: to identify and address any modifications of the games required for adaptation to diminished sensory abilities; to optimize training dosage and test timing of retention of effects; and to test and refine the battery of outcome assessments. Primary outcome assessment are tests of attention distraction (subtest from a Useful Field of View Test). This pilot will explore a number of secondary outcome measures including EEG and functional imaging biomarkers of change, measures of general cognitive improvement and measures of function including a driving simulator task.

Conditions

Cognitive Enhancement

Aging

Study ID

NCT03900702

Start date

Feb 15, 2019

Status verified date

Apr, 2019

Completion date

Sep, 2020

Anticipated

Primary completion date

May, 2020

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 60 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

1. age 60-80 years old
2. not demented
3. living independently; and (4) fluent in English.

Exclusion Criteria:

1. history of dementia, stroke, head injury involving loss of consciousness
2. current psychiatric or neurological disorders other than depression/anxiety

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Active Intervention

Gaze-driven games, played at home on PC with eye-tracker, to train resistance to attention distraction and speed of processing.

no intervention: Wait List Control

Wait list then cross over to active intervention.

Interventions

Gaze-driven training games

Training games are played on a PC with attached eye-tracker. Games include embedded training principles to improve attentional control including resistance to distraction and inhibitory control.

Primary outcome measure

  • UFOV Attention Distraction [ Time Frame: 12 weeks ]
  • UFOV Speed of Processing [ Time Frame: 12 weeks ]

Central Contacts and Locations

Central contacts

Anne M Engler, BA

8582461931amengler@ucsd.edu

Sarah Hacker, BA

8582461931shacker@ucsd.edu

Locations

Research on Autism and Development Lab, UCSD

Recruiting

La Jolla, California, United States, 92122

Contacts

Anne M Engler

858-246-1931amengler@ucsd.edu

Sarah Hacker

8582461931shacker@ucsd.edu

More Information

Sponsor

Jeanne Townsend, PhD

Last update posted

Apr 3, 2019

Last verified

Apr, 2019

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Jeanne Townsend, PhD on 2019-04-03.