Recruiting

Takotsubo Registry

Sponsor:

Cedars-Sinai Medical Center

Code:

NCT03910569

Conditions

Takotsubo Cardiomyopathy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The Cedars-Sinai SHI Takotsubo Registry and Proteomic Study is an observational registry that will collect retrospective and prospective demographic, clinical, hemodynamic, laboratory and other diagnostic parameters, therapy and outcome data from individuals who meet the inclusion/exclusion criteria of Takotsubo Registry protocol. Subjects will also be invited to provide a blood sample utilizing a Mitra kit sent to their homes. Researchers from the Barbra Streisand Women's Heart Center will analyze Registry data to identify Takotsubo phenotypes, improve diagnostic capabilities, better predict recurrence rates, and develop targeted Takotsubo treatments.

Conditions

Takotsubo Cardiomyopathy

Study ID

NCT03910569

Start date

Jan 3, 2019

Status verified date

Aug, 2026

Completion date

Feb, 2029

Anticipated

Primary completion date

Feb, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Have received a diagnosis of Takotsubo from their physician and consent to enroll
  • Submit full medical records needed for Takotsubo adjudication

Exclusion Criteria:

  • Younger than 18 years
  • Unable to provide informed consent
  • Unable to provide the necessary documentation needed for screening purposes

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Number of participants with Prevalence of the Takotsubo [ Time Frame: Baseline, Annual follow-up up to 30years ]
  • Number of participants with Recurrence the Takotsubo [ Time Frame: Baseline, Annual follow-up up to 30years ]
  • Annual update surveys will collect data on patient's prospective health status following Takotsubo event [ Time Frame: Baseline, Annual follow-up up to 30years ]
  • Risk factors affecting which patients, having had one Takotsubo event, will more likely experience a Takotsubo reoccurrence or related subsequent adverse event [ Time Frame: Baseline, Annual follow-up up to 30years ]

Central Contacts and Locations

Central contacts

TS Registry

310-248-8563takotsuboresearch@cshs.org

BS WHC, MS

310-423-9666bswhc.research@cshs.org

Locations

Cedars Sinai Medical Center

Recruiting

Los Angeles, California, United States, 90005

More Information

Sponsor

Cedars-Sinai Medical Center

Last update posted

Aug 19, 2026

Last verified

Aug, 2026

Keywords

  • Takotsubo

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Cedars-Sinai Medical Center on 2026-08-19.