Recruiting

Dyadic Yoga

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT03948100

Conditions

Esophageal Carcinoma

Lung Non-Small Cell Carcinoma

Stage I Lung Cancer AJCC v8

Stage IA1 Lung Cancer AJCC v8

Stage IA2 Lung Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Educational Intervention

Quality-of-Life Assessment

Questionnaire Administration

Yoga

Study Details

Brief summary:

This trial studies how well dyadic yoga intervention works in improving physical performance and quality of life in patients with stage I-IV non-small cell lung or esophageal cancer undergoing radiotherapy and their caregivers. Dyadic yoga intervention may help to improve physical function, fatigue, sleep difficulties, depressive symptoms, and overall quality of life for patients with non-small cell lung cancer and/or their caregivers.

Conditions

Esophageal Carcinoma

Lung Non-Small Cell Carcinoma

Stage I Lung Cancer AJCC v8

Stage IA1 Lung Cancer AJCC v8

Stage IA2 Lung Cancer AJCC v8

Study ID

NCT03948100

Start date

Dec 20, 2018

Status verified date

Apr, 2026

Completion date

Apr 30, 2027

Anticipated

Primary completion date

Apr 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • PATIENT ONLY: Diagnosed with stage I-IV non-small cell lung cancer (NSCLC) or esophageal cancer and going to receive at least 3 weeks of thoracic radiotherapy (RT)
  • PATIENT ONLY: Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 2
  • PATIENT ONLY: Able to read, write and speak English
  • PATIENT ONLY: Able to provide informed consent
  • PATIENT ONLY: Having a family caregiver (e.g., spouse, sibling, adult child) who assists the patient during the cancer treatment (e.g., emotional support, transportation, meal preparation, care coordination, etc) per patient self-report. Note, patients must identify a family caregiver; however, the participation of the family caregiver is optional. For caregivers to be eligible, they must be at least 18 years old; able to read, write and speak English; and able to provide informed consent. Family caregivers may consent to participate in the intervention and caregiver assessments or only the assessments based on their preference.

Exclusion Criteria:

  • PATIENT ONLY: Who have regularly (self-defined) participated in a mind-body practice in the year prior to diagnosis
  • PATIENT ONLY: Patients who metastatic disease involving the central nervous system

Study Design

Enrollment

400 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Group I (dyadic yoga)

Patients and caregivers undergo dyadic yoga intervention session involving physical exercises and relaxation techniques over 60 minutes each for up to 15 sessions.

active comparator: Group II (dyadic education)

Patients and caregivers undergo dyadic education program session focusing on strategies of how to manage patient and caregiver symptoms over 60 minutes each for up to 15 sessions.

Interventions

Educational Intervention

Undergo dyadic education program

Quality-of-Life Assessment

Ancillary studies

Questionnaire Administration

Ancillary studies

Yoga

Undergo dyadic yoga

Primary outcome measure

  • Patient 6-minute walk test (6MWT) [ Time Frame: At 3 months post study ]

Central Contacts and Locations

Central contacts

Kathrin Milbury

713-745-2868kmilbury@mdanderson.org

Locations

M D Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Kathrin Milbury

713-745-2868kmilbury@mdanderson.org

Principal Investigator:

Kathrin Milbury

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Apr 15, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-04-15.