Recruiting

Clinical Decision Support

Sponsor:

Intermountain Health Care, Inc.

Code:

NCT03984175

Conditions

Acute Respiratory Distress Syndrome

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Implementation of Processes

Study Details

Brief summary:

Perform a pilot study of quality improvement interventions for critical care physicians (intensivists) and respiratory therapists (RTs) to improve application of low tidal volume mechanical ventilation (LTVV) for patients with the acute respiratory distress syndrome (ARDS) using the computerized mechanical ventilation protocols currently available in the investigator's Cerner electronic health record (EHR).

Conditions

Acute Respiratory Distress Syndrome

Study ID

NCT03984175

Start date

Jul 8, 2018

Status verified date

Aug, 2022

Completion date

Dec 23, 2022

Anticipated

Primary completion date

Dec 23, 2022

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Invasive mechanical ventilation
2. PF ratio <255
3. Bilateral infiltrates on chest radiograph (adjudicated by a co-investigator)
4. Presence of ≥1 risk factor for ARDS as determined by review of the HER

Exclusion Criteria:

1. Age <18 years
2. Pulmonary capillary wedge pressure >18 mm Hg if a right heart catheter is present
3. Prisoner
4. Known to be pregnant
5. Death <24 hours from initial intubation
6. Placed comfort care <24 hours from initial intubation
7. Mechanically ventilated for >7 days prior to meeting ARDS criteria

Study Design

Enrollment

350 participants

Anticipated

Intervention Model

Single group

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Patients with ARDS at three Intermountain tertiary hospitals

Interventions

Implementation of Processes

Implementation of processes to improve compliance with low tidal volume ventilation in patients with ARDS using a computerized protocol

Primary outcome measure

  • LTVV Compliance [ Time Frame: through study completion - 6 months ]

Central Contacts and Locations

Central contacts

Colin K Grissom, MD

801-507-6554colin.grissom@imail.org

Locations

Intermountain Medical Center

Recruiting

Murray, Utah, United States, 84107

Contacts

Valerie Aston

801-507-4606valerie.aston@imail.org

Carlos Barbagelata

801-507-4607carlos.barbagelata@imail.org

More Information

Sponsor

Intermountain Health Care, Inc.

Last update posted

Aug 3, 2022

Last verified

Aug, 2022

Keywords

  • ARDS
  • Lung Protective Mechanical Ventilation
  • Clinical Decision Support

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-27. This information was provided to ClinicalTrials.gov by Intermountain Health Care, Inc. on 2022-08-03. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.