Recruiting

Deep Brain Stimulation

Sponsor:

Washington University School of Medicine

Code:

NCT03992625

Conditions

Parkinson Disease

Essential Tremor

Dystonia

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Interventions

Deep Brain Stimulation

Study Details

Brief summary:

The object of this study is to longitudinally collect clinical outcomes of patients receiving deep brain stimulation for movement disorders with the objective of making retrospective comparisons and tracking of risks, benefits, and complications.

Conditions

Parkinson Disease

Essential Tremor

Dystonia

Study ID

NCT03992625

Start date

Jan 3, 2011

Status verified date

Jun, 2019

Completion date

Jan 1, 2030

Anticipated

Primary completion date

Jan 1, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Levodopa responsive Parkinson disease OR
  • Medically refractory Essential Tremor OR
  • Medically refractory Dystonia

Exclusion Criteria:

  • Dementia (Mattis Dementia Rating Scale <130)
  • Structural abnormalities precluding intracranial surgery

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Interventions

Deep Brain Stimulation

High frequency electrical stimulation of deep brain nuclei for the treatment of movement disorders

Primary outcome measure

  • UPDRS [ Time Frame: Change in UPDRS at 1 year after DBS (from preoperative baseline). ]

Central Contacts and Locations

Central contacts

Mwiza Ushe, M.D.

3143625262ushem@wustl.edu

Locations

Washington University in St Louis

Recruiting

Saint Louis, Missouri, United States, 63110

Contacts

Mwiza Ushe, M.D.

314-362-5262ushem@wustl.edu

More Information

Sponsor

Washington University School of Medicine

Last update posted

Jun 20, 2019

Last verified

Jun, 2019

Keywords

  • Deep brain stimulation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Washington University School of Medicine on 2019-06-20.