Recruiting

Web-Based Interventions

Sponsor:

Child Mind Institute

Code:

NCT04066985

Conditions

Depression

Depressive Disorder

Behavioral Symptoms

Mood Disorders

Mental Disorders

Eligibility Criteria

Sex: All

Age: 11 - 17

Healthy Volunteers: Accepted

Interventions

Growth Mindset Online Single-Session Program

Self-Kindness Online Single-Session Program

Supportive Therapy Online Single-Session Program (Control)

Study Details

Brief summary:

Major depression (MD) in youth is a serious psychiatric illness with extensive morbidity and mortality. The American Academy of Pediatrics recently released practice guidelines promoting primary care (PC)-based youth MD screening; however, even when diagnosed by PC providers, <50% of youth with MD access treatment. Thus, a need exists for interventions that are feasible for youths and parents to access and complete-and that may strengthen parents' likelihood of pursuing longer-term services. Single-session interventions (SSIs) may help forward these goals. SSIs include elements of comprehensive treatments, but their brevity makes them easier to disseminate at scale. Meta-analytic evidence suggests SSIs can reduce youth psychopathology, including self-administered (e.g., online) SSIs. One computer-based SSI, teaching growth mindset (GM; viewing personal traits as malleable), has reduced adolescent depressive symptoms in multiple RCTs. A second computer-based SSI was recently developed to reduce youth depressive symptoms via targeting reductions in self-hate-a symptom identified as important for the maintenance of other depressive symptoms in teenagers. This study will test whether either the growth mindset SSI (GM-SSI), the self-kindness SSI (SK-SSI), or both SSIs reduce symptoms of depression in adolescents, relative to an active "supportive therapy" SSI, which teaches adolescents to share their emotions with trusted others. Youths participating in existing research through the Healthy Brain Network (N=501) will receive either the growth mindset SSI (GM-SSI), the self-kindness SSI (SK-SSI), or the supportive therapy SSI (ST-SSI). The investigators will examine whether the GM-SSI and/or the SK-SSI, versus the ST-SSI will reduce youth depressive symptoms across three months. Results may identify two novel, potent, and brief interventions for adolescent depressive symptoms.

Conditions

Depression

Depressive Disorder

Behavioral Symptoms

Mood Disorders

Mental Disorders

Study ID

NCT04066985

Start date

Oct 1, 2019

Status verified date

Oct, 2019

Completion date

Oct 31, 2020

Anticipated

Primary completion date

Oct 31, 2020

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 11 - 17

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy Brain Network study participants
  • Between the ages of 11-17 (inclusive)
  • Fluent in English

Exclusion Criteria:

  • Youth with parent-reported intellectual disability

Study Design

Enrollment

501 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Growth Mindset Intervention

Includes one online, single-session program, the Growth Mindset Program. The 30-minute, self-administered youth program includes: An introduction to the brain and a lesson on neuroplasticity; Testimonials from older youths who describe their views that traits are malleable, due to the brain's plasticity; Further stories by older youths, describing times when they used "growth mindsets" to persevere during social/emotional setbacks; Study summaries noting how/why personality can change; And an exercise in which youths write notes to younger students, using scientific information to explain people's capacity for change.

experimental: Self-Kindness Intervention

Includes one online, single-session program, the Self-Kindness Program. The 30-minute, self-administered youth program includes: An introduction to the science behind why adolescents might think disliking themselves is necessary for success and thus fear self-compassion; Scientific evidence and testimonials from other teens that being self-compassionate actually predicts being more successful socially and academically; Evidence-based tips for overcoming common, fear of self-compassion based obstacles to self-compassion in day to day life; And an exercise in which youths write notes to younger students, using scientific information to explain the benefits of using self-kindness.

active comparator: Supportive Therapy Intervention

Includes one online, single-session active comparator program, the Supportive Therapy Intervention. The ST SSI is designed to control for nonspecific aspects of intervention, including engagement in a computer program. The 30-minute, self-administered control group program includes: vignettes written by older youths who describe times when they benefited from sharing their feelings with friends or family; the same number of reading and writing activities as the web-based growth mindset intervention. However, the only goals of the ST intervention are to encourage youths to identify and express feelings to close others; the intervention does not teach or emphasize specific skills or beliefs.

Interventions

Growth Mindset Online Single-Session Program

30minute self-administered program for youths

Self-Kindness Online Single-Session Program

30minute self-administered program for youths

Supportive Therapy Online Single-Session Program (Control)

30minute self-administered active comparator program for youths

Primary outcome measure

  • Change in Mood and Feelings Questionnaire; Youth-Report [ Time Frame: [Baseline to 3-month follow-up.] ]

Central Contacts and Locations

Central contacts

Locations

Child Mind Institute

Recruiting

New York, New York, United States, 10022

Contacts

More Information

Sponsor

Child Mind Institute

Last update posted

Oct 4, 2019

Last verified

Oct, 2019

Keywords

  • Depression
  • Adolescent
  • Therapeutics
  • Mental Health

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Child Mind Institute on 2019-10-04.